ReviewFrontiers in oral health2025
Hypovitaminosis and its association with recurrent aphthous stomatitis: a comprehensive review of clinical correlations and diagnostic considerations.
Review in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From systemic immune dysregulation to oral disease: evidence linking food allergies and oral manifestations- a systematic review.BMC oral health · 2026Pooled it
- A systematic review and meta-analysis of single-application topical doxycycline for recurrent aphthous stomatitis.The Saudi dental journal · 2026Article
- Prevalence, risk factors, and psychosocial impact of self-reported recurrent oral ulceration among Palestinian medical and dental students: a multicenter cross-sectional study.BMC oral health · 2026Article
- Pain severity trajectory and influencing factors in children with recurrent aphthous stomatitis: a latent variable growth mixture model.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Patient with Inflammatory Bowel Disease in a Dental Office-Which Antibiotic to Choose?-Narrative Review.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hypovitaminosis, or vitamin deficiency, has been increasingly recognized as a potential contributing factor in the development of recurrent aphthous stomatitis (RAS), a condition characterized by the periodic formation of painful ulcers in the oral mucosa. Materials and methods: This mini review includes a literature search on PubMed, Web of Science, and Scopus databases using keywords "hypovitaminosis AND aphthous ulcers." Results: There is a growing body of evidence supporting the link between various vitamin deficiencies-particularly vitamins B12, C, and folate-and the prevalence of RAS, with implications for both diagnosis and management. Conclusion: This review aims to outline the clinical and biochemical findings associated with hypovitaminosis in individuals presenting with RAS, emphasizing the diagnostic importance of recognizing vitamin deficiencies in these patients and exploring possible therapeutic approaches.
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Registered trials
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