Evidence map›Paper›PMID 39935699›Full record

ArticleJournal of hematology2025

A Rare Case of Acute Aleukemic Mast Cell Leukemia With Osteoblastic Lesions in the Appendicular Skeleton.

Muralidhar Idamakanti, Ala Ebaid, Rani Indrani Bijjam, Alexei Bakhirev, Shiva Kumar Mukkamalla, Leslie Andritsos

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muralidhar IdamakantiAdult Internal Medicine Services (AIMS), Presbyterian Healthcare Services (PHS), Albuquerque, NM 87106, USA.ORCID https://orcid.org/0009-0004-3599-3003
Ala EbaidDivision of Hematology/Oncology, The University of New Mexico Comprehensive Cancer Center (UNMCC), Albuquerque, NM 87102, USA.
Rani Indrani BijjamAdult Internal Medicine Services (AIMS), Presbyterian Healthcare Services (PHS), Albuquerque, NM 87106, USA.
Alexei BakhirevPathology Associates of Albuquerque (PAA), Albuquerque, NM 87106, USA.
Shiva Kumar MukkamallaHematology/Medical Oncology, UPMC Hillman Cancer Center, Indiana, PA 15701, USA.
Leslie AndritsosDivision of Hematology/Oncology, The University of New Mexico Comprehensive Cancer Center (UNMCC), Albuquerque, NM 87102, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cell leukemia (MCL) is a rare and aggressive form of systemic mastocytosis (SM) that commonly involves the bone. This often presents as osteoporosis with focal osteolytic lesions and pathological fractures. Osteoblastic (sclerotic) lesions are rarely seen in MCL. The vertebral bodies are the most common site of bone involvement, with lesions outside of the axial skeleton being extremely rare. MCL presenting with osteoblastic lesions has been reported in the literature, however, there are no reported cases of osteoblastic lesions in the appendicular skeleton. Here we report a rare case of acute aleukemic MCL that presented with diffuse osteoblastic/sclerotic osseous lesions involving ribs, thoracic spine, lumbar spine and pelvis without pathological fractures.

Indexed as

Aleukemic mast cell leukemiaMast cell leukemiaOsteoblastic osseous lesionsOverall survivalSystemic mastocytosisTyrosine kinase inhibitors

Identifiers

PMID39935699
PMCPMC11809598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.