Evidence map›Paper›PMID 39935661›Full record

ArticleClinical case reports2025

The Occult Insulinoma Was Localized Using Endoscopic Ultrasound Guidance: A Case Report.

Zhongqiu Guo, Yanrong Chen, Ronghuo Liu, Yuhua Chen

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhongqiu GuoDepartment of Endocrinology and Metabolism, Longgang District People's Hospital of Shenzhen The Second Affiliated Hospital of the Chinese University of Hong Kong, Longgang Central City Shenzhen Guangdong People's Republic of China.
Yanrong ChenDepartment of Endocrinology and Metabolism, Longgang District People's Hospital of Shenzhen The Second Affiliated Hospital of the Chinese University of Hong Kong, Longgang Central City Shenzhen Guangdong People's Republic of China.ORCID https://orcid.org/0000-0002-2878-2919
Ronghuo LiuDepartment of Endocrinology and Metabolism, Longgang District People's Hospital of Shenzhen The Second Affiliated Hospital of the Chinese University of Hong Kong, Longgang Central City Shenzhen Guangdong People's Republic of China.
Yuhua ChenDepartment of Endocrinology and Metabolism, Longgang District People's Hospital of Shenzhen The Second Affiliated Hospital of the Chinese University of Hong Kong, Longgang Central City Shenzhen Guangdong People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulinomas are the primary etiology of endogenous hyperinsulinemic hypoglycemia, which often manifest with Whipple's triad and neuroglycopenic symptoms. Given the diverse clinical manifestation and subtle onset of insulinomas generally in a small size, detecting a minority of these generally small tumors can be challenging. We reported a case of a 44-year-old female patient with recurrent hypoglycemia accompanied by hyperinsulinemia, and the conventional imaging revealed no abnormality. With the aid of endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB), the insulinoma was precisely diagnosed and localized, and successfully excised via operation. The patient's hyperinsulinemia and hypoglycemic episodes were relieved significantly after surgery. The application of EUS-FNAB notably enhances the diagnostic accuracy for occult insulinomas, thereby informing appropriate surgical management. Herein, we advocate for invasive EUS examination in patients exhibiting strong clinical and laboratory indicators of insulinoma, even when conventional imaging results are negative.

Indexed as

endoscopic ultrasoundfine needle aspiration biopsy techniquehypoglycemiainsulinoma

Identifiers

PMID39935661
PMCPMC11810623

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