Evidence map›Paper›PMID 39934916›Full record

ArticleArchives of public health = Archives belges de sante publique2025

Home-based urinary HPV self-sampling for the detection of cervical cancer precursor lesions: attitudes and preferences from Belgian females participating in the CASUS study.

Jhana O Hendrickx, Severien Van Keer, Gilbert Donders, Steven Weyers, Jean Doyen, Koen C L Beyers, Alejandra Rios-Cortes, Nette Meers, Laura Téblick, Vanessa V J Vankerckhoven

Registry-linked trialAbstract read
In one paragraph

Article in Archives of public health = Archives belges de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04530201 (Developing a Complete Cervical Cancer Screening Solution Based on First-void Urine Self-sampling), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04530201 nacompletednot on this map

Developing a Complete Cervical Cancer Screening Solution Based on First-void Urine Self-sampling: Validation for Detection of Precursor Lesions

TypeinterventionalSponsorUniversiteit AntwerpenRan2020 to 2022Enrolled332ConditionsCervical Cancer, Cervical Intraepithelial Neoplasia, Human Papilloma Virus, HPV-Related Cervical CarcinomaArmsColli-Pee Small Volumes (10 mL) device
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jhana O HendrickxNovosanis, Bijkhoevelaan 32c, Wijnegem, 2110, Belgium. jhana_h@hotmail.com.
Severien Van KeerVaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Drie Eikenstraat 663, Edegem (Antwerp), 2650, Belgium.
Gilbert DondersDepartment of Obstetrics and Gynaecology of the General Regional Hospital Heilig Hart, Kliniekstraat 45, Tienen, 3300, Belgium.
Steven WeyersDepartment of Obstetrics and Gynecology, Ghent University Hospital, Corneel Heymanslaan 10, Ghent, 9000, Belgium.
Jean DoyenDepartment Gynaecology-Obstetrics, University Hospital Liège, Avenue de L'Hôpital 1, Liège, 4000, Belgium.
Koen C L BeyersNovosanis, Bijkhoevelaan 32c, Wijnegem, 2110, Belgium.
Alejandra Rios-CortesNovosanis, Bijkhoevelaan 32c, Wijnegem, 2110, Belgium.
Nette MeersNovosanis, Bijkhoevelaan 32c, Wijnegem, 2110, Belgium.
Laura TéblickVaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Drie Eikenstraat 663, Edegem (Antwerp), 2650, Belgium.
Vanessa V J VankerckhovenNovosanis, Bijkhoevelaan 32c, Wijnegem, 2110, Belgium.

Funding

H2020 Eurostars 12396Research Foundation-Flanders 1240220N
6 · The paper itself

Abstract

backgroundCervical cancer (CC) is the fourth most common cancer globally in females, caused by oncogenic infections with high-risk human papillomavirus (hrHPV) strains. Successful CC screening programs strongly depend on the participation rate of the target population. Nevertheless, it remains challenging to reach under screened populations. The CASUS study aimed to develop a complete CC screening solution based on first-void urine (FVU) self-sampling. Here we report on the usability perceptions and preferences from females that participated in the CASUS study by collecting FVU as a liquid biopsy.

methodsFemales self-collected FVU samples at home the day before colposcopy using the Colli-Pee

resultsA total of 332 females (26-70y) were enrolled in the CASUS study of which 210 completed the questionnaire. Overall, 66.6% of females preferred FVU self-sampling over a physician taken cervical sample (PTS) (32.9%) for their next CC screening. Out of 159 women who reported prior experience with a urine cup, 79.2% expressed a preference for using the Colli-Pee

conclusionThe results of this study show that the majority of females in this referral cohort would prefer to self-collect a FVU sample at-home over a PTS for their next CC screening. Moreover, Colli-Pee

trial registrationThe CASUS study was registered in http://www. CLINICALTRIALS: gov (identifier: NCT04530201).

Indexed as

AtitudesCASUSCervical cancer screeningFirst-void urineHPVPreferencesSelf-sampling

Identifiers

PMID39934916
PMCPMC11818055

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.