Evidence map›Paper›PMID 39934885›Full record

ArticleJournal of orthopaedic surgery and research2025

Texture analysis of T1- and T2-weighted images identifies myofiber atrophy and grip strength decline in streptozotocin-induced type 1 diabetic sarcopenia rats.

Dong Xing, Fang Liu, Yufan Gao, Ziyan Fei, Yunfei Zha

Abstract read
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In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Serum parathyroid hormone and risk of sarcopenia: a meta-analysis.Journal of orthopaedic surgery and research · 2025
    Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong Xing *Department of Radiology, Renmin Hospital of Wuhan University, 99, Zhangzhidong Rd, Wuhan, 430060, People's Republic of China.
Fang Liu *Department of Radiology, Renmin Hospital of Wuhan University, 99, Zhangzhidong Rd, Wuhan, 430060, People's Republic of China.
Yufan GaoDepartment of Radiology, Renmin Hospital of Wuhan University, 99, Zhangzhidong Rd, Wuhan, 430060, People's Republic of China.
Ziyan FeiDepartment of Radiology, Renmin Hospital of Wuhan University, 99, Zhangzhidong Rd, Wuhan, 430060, People's Republic of China.
Yunfei ZhaDepartment of Radiology, Renmin Hospital of Wuhan University, 99, Zhangzhidong Rd, Wuhan, 430060, People's Republic of China. zhayunfei999@126.com.

Funding

Enshi Prefecture Science and Technology Project D20220032Fundamental Research Funds for the Central Universities 2042022kf1102National Natural Science Foundation of China 81801670National Natural Science Foundation of China 82171895
6 · The paper itself

Abstract

backgroundType 1 diabetes mellitus is associated with accelerated skeletal muscle aging and sarcopenia, a condition characterized by muscle mass and function loss. Early and noninvasive evaluation of muscle microstructural damage is critical for managing sarcopenia in diabetes. This study evaluated the potential of MRI texture analysis as a noninvasive imaging tool to assess myofiber size and grip strength alterations in a rat model of diabetic sarcopenia. MATERIALS AND

methodsTwenty SD rats were randomly and evenly allocated to the control (CON) and diabetic sarcopenia (DS) groups. Blood glucose, body weight, and forelimb grip strength were measured weekly. In the eighth week, axial T

resultsThe DS group presented significant reductions in body weight, grip strength, and myofiber size (p < 0.001). Seven texture features demonstrated high repeatability. Among them, T

conclusionMuscle texture analysis based on T

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Hand StrengthMagnetic Resonance ImagingMuscle Fibers, SkeletalSarcopeniaAnimalsMaleMuscle, SkeletalRatsRats, Sprague-DawleyStreptozocinStreptozocinMagnetic resonance imagingMuscle strengthMyofiber atrophySarcopeniaSkeletal muscleTexture analysis

Identifiers

PMID39934885
PMCPMC11817564

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.