Evidence map›Paper›PMID 39934855›Full record

ArticleItalian journal of pediatrics2025

Impact of intravenous immunoglobulin treatment on peripheral blood cells in children with Kawasaki disease complicated with coronary artery lesion.

Junshan Zhao, Yingying Ma, Li Xin, Lijun Wang, Hongliang Gao

Abstract read
In one paragraph

Article in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junshan ZhaoDepartment of Intensive Care Medicine Division 2, Hebei Children's Hospital, Shijiazhuang City, 050031, China. zhaojs_026@sina.com.
Yingying MaDepartment of Intensive Care Medicine Division 2, Hebei Children's Hospital, Shijiazhuang City, 050031, China.
Li XinDepartment of Intensive Care Medicine Division 2, Hebei Children's Hospital, Shijiazhuang City, 050031, China.
Lijun WangDepartment of Intensive Care Medicine Division 2, Hebei Children's Hospital, Shijiazhuang City, 050031, China.
Hongliang GaoDepartment of Intensive Care Medicine Division 2, Hebei Children's Hospital, Shijiazhuang City, 050031, China.

Funding

Hebei Province 2023 medical science research project 20231174
6 · The paper itself

Abstract

backgroundKawasaki disease (KD) primarily affects young children and can lead to coronary artery lesions. Intravenous immunoglobulin (IVIG) treatment is essential; however, it may fail in 10-20% of cases, increasing the risk of complications. Complete blood count (CBC) tests can help assess disease severity and predict risks. This study investigated the impact of IVIG on peripheral blood cells, including neutrophil count, platelet-lymphocyte ratio, hemoglobin level, mean platelet volume (MPV), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP), in children with KD complicated by coronary artery lesions (CALs).

methodsThis retrospective analysis included children diagnosed with typical KD. The neutrophil count, hemoglobin level, platelet-lymphocyte ratio, MPV, ESR, and CRP were compared between those with (CAL

resultsA total of 76 children with KD were analyzed, including 30 with CAL

conclusionsAfter IVIG treatment, CAL

Indexed as

Coronary Artery DiseaseImmunoglobulins, IntravenousImmunologic FactorsMucocutaneous Lymph Node SyndromeBlood Cell CountChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesTreatment OutcomeImmunoglobulins, IntravenousImmunologic FactorsCoronary arteriesIntravenous immunoglobulinKawasaki diseasePeripheral blood cells

Identifiers

PMID39934855
PMCPMC11816787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.