Evidence map›Paper›PMID 39934717›Full record

ArticleBMC cancer2025

A clinical study on microwave ablation of T1N0M0 papillary thyroid carcinoma locating in dangerous region.

Hui-di Zhou, Ying Wei, Zhen-Long Zhao, Lili Peng, Yan Li, Ming-An Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hui-di ZhouDepartment of Ultrasound Medicine, Union Hospital, Tongji Medical College, Clinical Research Center for Medical Imaging in Hubei Province, Huazhong University of Science and Technology, Wuhan, China.
Ying WeiDepartment of Interventional Medicine, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing, 100029, China.
Zhen-Long ZhaoDepartment of Interventional Medicine, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing, 100029, China.
Lili PengDepartment of Interventional Medicine, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing, 100029, China.
Yan LiDepartment of Interventional Medicine, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing, 100029, China.
Ming-An YuDepartment of Interventional Medicine, China-Japan Friendship Hospital, No. 2 Yinghuayuan East Street, Chaoyang District, Beijing, 100029, China. yma301@163.com.

Funding

National High Level Hospital Clinical Research Funding Grant No. 2023-NHLHCRF-YYPP-TS-01National Natural Science Foundation of China 62176268
6 · The paper itself

Abstract

To evaluate the feasibility, safety and efficiency of the microwave ablation (MWA) of T1N0M0 papillary thyroid carcinoma (PTC) locating in dangerous region. This is a clinical retrospective study, and the data of patients who underwent thermal ablation for T1N0M0 PTC from June 2016 to March 2021 were reviewed. After ablation, the rates of technical success, as well as the changes in tumor size and volume, tumor disappearance, disease progression, and complications, were assessed. According to the tumor size, the patients were divided into T1a and T1b subgroups. There was a total of 94 cases enrolled in the present study. The mean age was 43.06 ± 11.51 years (22-65 years). The median follow-up time was 33 months (25-75% IQR 24-44; 12-85months). The technical success rate was 100%. Due to expanding ablation, the MD and volume of the ablation zone increased at the 1st and 3rd months and decreased from the 12th month after ablation (p < 0.05 for all). At the end of follow-up, the complete disappearance of ablation zone occurred in 78(78/94, 82.98%) cases, including 65 (65/75, 86.67%) cases in T1a subgroup and 13(13/19, 68.4%) cases in the T1b subgroup. There was no difference between the two subgroups (p = 0.121). 5 (5/94,5.3%) patients developed disease progression, and all of them were in T1a subgroup (5/75, 6.67%). There was not significantly different between two subgroups (p = 0.559). The complication rate was 15.96% (15/94). Recurrent laryngeal nerve (RLN) injury encountered in 11 (11/75, 14.7%) cases in the T1a subgroup and 4 (4/19, 21.1%) cases in the T1b subgroup. No significant difference between the two subgroups (p = 0.74). This preliminary study indicates that MWA is an effective treatment for T1N0M0 PTC locating in dangerous region.

Indexed as

Ablation TechniquesMicrowavesRadiofrequency AblationThyroid Cancer, PapillaryThyroid NeoplasmsAdultAgedFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesTreatment OutcomeDangerous regionMicrowave ablationRecurrent laryngeal nerve (RLN) injury

Identifiers

PMID39934717
PMCPMC11818028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.