ArticleBMC cardiovascular disorders2025
The new definition of metabolic syndrome including hyperuricemia improves its prognostic value: results from NHANES database.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- GPR75 mediates hyperuricemia-induced endothelial inflammatory injury via a HOTAIR/miR-141-3p regulatory network.Molecular biology reports · 2026Article
- Relationship Between Adipose Tissue and Liver Dysfunction in Women with Polycystic Ovary Syndrome and Metabolic Syndrome.Metabolites · 2026Review
- Uric acid, vitamin D, and left ventricular hypertrophy: Unveiling cardiovascular risks - a retrospective cross-sectional study.Medicine · 2026Article
- Hyperuricemia as a Biomarker for Circadian Syndrome: A Cross-Sectional Study.Clocks & sleep · 2026Article
- Association of ABCG2 gene variants with urate levels in Mexican patients with type 2 diabetes and chronic kidney disease.Scientific reports · 2026Article
- Temporal Sequence of Metabolic Syndrome Components: Abdominal Obesity as the Primary Driver of Progression in a Korean Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- Effectiveness of Physical Activity-Led Workplace Health Promotion Interventions: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
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Authors and funding
6 authors.
Funding
Abstract
backgroundMetabolic syndrome (MetS) is a significant global health issue that is strongly associated with an increased risk of cardiovascular disease (CVD). While MetS was initially proposed to identify more high-risk individuals and facilitate early management, hyperuricemia has not yet been included in its definition, despite its strong association with MetS. This study aims to explore the prognostic value of incorporating hyperuricemia into the definition of MetS.
methodsData derived from the National Health and Nutrition Examination Survey (NHANES) conducted between 1999 and 2018 were analyzed. The old version of MetS (MetS
resultsAmong the 36,363 participants analyzed, 12,594 (34.6%) and 14,137 (38.9%) met MetS
conclusionsThe inclusion of hyperuricemia in the MetS criteria could identify a larger proportion of individuals at metabolic risk, thereby facilitating early management to prevent long-term adverse events.
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