Evidence map›Paper›PMID 39934693›Full record

ArticleBMC cardiovascular disorders2025

Inverse association between CALLY index and angina pectoris in US adults: a population-based study.

Jing Ye, Liping Chen, Donge Xu, Rui Li, Rongwei Lan, Shuaiqing Chen, Xinyao He, Mingshen Lin

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing YeLishui Traditional Chinese Medicine Hospital, Lishui, China.
Liping ChenLishui Traditional Chinese Medicine Hospital, Lishui, China.
Donge XuTongde Hospital of Zhejiang Province, Hangzhou, China.
Rui LiLishui Traditional Chinese Medicine Hospital, Lishui, China.
Rongwei LanLishui Traditional Chinese Medicine Hospital, Lishui, China.
Shuaiqing ChenLishui Traditional Chinese Medicine Hospital, Lishui, China.
Xinyao HeLishui Traditional Chinese Medicine Hospital, Lishui, China.
Mingshen LinDepartment of Clinical Laboratory, Lishui Municipal Central Hospital, Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, China. linmingshen@wmu.edu.cn.

Funding

Lishui City Medical Key Discipline of Chinese Medicine and Cardiovascular Disease 2022ZDXK002
6 · The paper itself

Abstract

backgroundThe C-reactive protein-albumin-lymphocyte (CALLY) index is a significant marker that reflects both inflammatory and nutritional states and has proven to be a valuable tool for assessing prognosis in various medical conditions. However, the connection between it and angina pectoris has not yet been fully examined. This research sought to thoroughly investigate the possible link between the CALLY index and angina pectoris.

methodsThis research utilized a cross-sectional approach, drawing data from the 2003-2010 National Health and Nutrition Examination Survey (NHANES), which included 16,291 adults from the U.S. The CALLY index was calculated based on lymphocyte counts, serum albumin concentrations, and C-reactive protein (CRP) levels. The relationship between the CALLY index and angina pectoris was analyzed using multivariate logistic regression and restricted cubic spline (RCS) methods. Subgroup and interaction analyses were also performed.

resultsElevated ln CALLY was inversely correlated with the prevalence of angina (OR: 0.88, 95% CI: 0.82, 0.95). Those in the highest quartile of the ln CALLY (Q4) were 38% less likely to experience angina than those in the lowest quartile (Q1) (OR: 0.62, 95% CI: 0.46, 0.84). RCS analysis revealed an L-shaped curve linking the CALLY index to angina, with a cutoff at 14. The consistency of this relationship was substantiated through subgroup analyses across different population groups.

conclusionsThis research highlights a notable inverse relationship between the CALLY index and angina in U.S. adults, suggesting its potential as an innovative tool for evaluating angina.

Indexed as

Angina PectorisC-Reactive ProteinInflammation MediatorsLymphocytesSerum Albumin, HumanAdultAgedBiomarkersCross-Sectional StudiesFemaleHumansLymphocyte CountMaleMiddle AgedNutritional StatusNutrition SurveysALB protein, humanBiomarkersC-Reactive ProteinInflammation MediatorsSerum Albumin, Human

Identifiers

PMID39934693
PMCPMC11816972

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