Evidence map›Paper›PMID 39934662›Full record

Observational studyBMC infectious diseases2025

Investigation of renal function in patients with long COVID in the Amazon region: a cross-sectional study.

Gabriela Maria Coimbra Coelho de Assis, Ian Gonçalves da Veiga, Rita de Nazaré Rayol Reis, Daniel Carvalho de Menezes, Stanley Soares Xavier, Elem Cristina Rodrigues Chaves, Jorge Rodrigues de Sousa, Juarez Antônio Simões Quaresma, Luiz Fábio Magno Falcão, Patrícia Danielle Lima de Lima

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriela Maria Coimbra Coelho de AssisDepartment of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Ian Gonçalves da VeigaDepartment of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Rita de Nazaré Rayol ReisDepartment of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Daniel Carvalho de MenezesDepartment of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Stanley Soares XavierDepartment of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Elem Cristina Rodrigues ChavesDepartment of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Jorge Rodrigues de SousaDepartment of Morphology and Physiological Sciences (DMCF), State University of Pará (UFPA), Belém, Pará, 66087-670, Brazil.
Juarez Antônio Simões Quaresma *Department of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Luiz Fábio Magno Falcão *Department of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil.
Patrícia Danielle Lima de Lima *Department of Center for Biological Health Sciences (CCBS), State University of Pará (UEPA), Belém, Pará, 66087-670, Brazil. patricia.lima@uepa.br.ORCID https://orcid.org/0000-0002-1068-2813

Funding

Amazon Foundation for Research Support (FAPESPA) #006/2020Conselho Nacional de Desenvolvimento Científico e Tecnológico-Brazil INCT:406360/2022-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brazil (CAPES) 13/2020'Secretary of Science, Technology, and Higher, Professional, and Technological Education (SECTET) #09/2021
6 · The paper itself

Abstract

backgroundCOVID-19 became a pandemic disease in 2020, with multisystem involvement and high renal morbidity during the acute phase. Some affected patients began to present new or persistent symptoms in a condition known as Long COVID. The study aimed to evaluate renal function using clinical and laboratory findings, and to establish the frequency and staging of renal function decline in Long COVID patients, as well as the associated factors.

methodsThis is a cross-sectional observational study that selected participants from a Long COVID clinical care program between 2020 and 2022.

resultsA total of 246 patients were selected for this study, and renal function decline was found in 83 (33.7%). Patients over 60 years (29.6%) and those who developed glycaemic alterations (41.8%) exhibited a higher prevalence of renal outcomes in long COVID. Some laboratory test as LDH levels and glycated hemoglobin seems to have a statistic relation with a decrease in renal function (p < 0.05).

conclusionA decline in renal function was common in patients with Long COVID in this study, and older age and glycaemic alterations were relevant to this condition. Some laboratory markers can be used to predict this outcome.

Indexed as

COVID-19KidneyAdultAgedAged, 80 and overBrazilCross-Sectional StudiesFemaleGlycated HemoglobinHumansKidney Function TestsMaleMiddle AgedSARS-CoV-2Glycated HemoglobinAcute kidney injuryLaboratory markersLong COVIDRenal function

Identifiers

PMID39934662
PMCPMC11817966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.