Evidence map›Paper›PMID 39934647›Full record

ArticleScientific reports2025

Genomic correlation, shared loci, and causal association between obesity, periodontitis and tooth loss.

Lin Chen, Yang Qu, Huijie Cui, Wenqiang Zhang, Xuan Wu, Xunying Zhao, Jinyu Xiao, Mingshuang Tang, Yutong Wang, Yanqiu Zou and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Shared genetic associations between CHAInternational journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Lin ChenDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Yang QuDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Huijie CuiDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Wenqiang ZhangDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Xuan WuDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Xunying ZhaoDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Jinyu XiaoDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Mingshuang TangDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Yutong WangDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Yanqiu ZouDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Lingli QiuDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Zhixin TanDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Bowen LeiDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Xiaofeng MaDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Di ZhangDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Yunjie LiuDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Mengyu FanDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Jiayuan LiDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China.
Ben ZhangDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China. benzhang@vip.163.com.
Xia JiangDepartment of Epidemiology and Biostatistics, Institute of Systems Epidemiology, West China School of Public Health and West China Fourth Hospital, China-PUMC C. C. Chen Institute of Health, Sichuan University, Chengdu, Sichuan, China. xiajiang@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Observational studies have reported an association of obesity with periodontitis and tooth loss, yet findings remain inconsistent. We aim to investigate the genetic link underlying obesity-related traits (BMI [body mass index], WHR [waist-to-hip ratio], WHR

Indexed as

Genetic Predisposition to DiseaseObesityPeriodontitisTooth LossBody Mass IndexFemaleGenome-Wide Association StudyGenomicsHumansLinkage DisequilibriumMaleMendelian Randomization AnalysisPhenotypePolymorphism, Single NucleotideGenetic correlationMendelian randomizationObesityPeriodontitisPleiotropic loci

Identifiers

PMID39934647
PMCPMC11814315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.