Evidence map›Paper›PMID 39934634›Full record

ArticlePhysical activity and nutrition2024

A review of sarcopenia pathogenesis and therapeutic approaches: resistance exercise, nutrition, and monoterpenes.

Sangmoon Lee, Suji Baek, Hangyul Park, Kang Han, Kang Pa Lee, Sang Hyun Ahn

Abstract read
In one paragraph

Article in Physical activity and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sangmoon LeeDepartment of Korean Medicine, graduate school of Korean medicine, Semyung University, Jecheon, Republic of Korea.
Suji BaekResearch and Development Center, UMUST R&D Corporation, Los Angeles, USA.
Hangyul ParkResearch and Development Center, UMUST R&D Corporation, Los Angeles, USA.
Kang HanResearch and Development Center, UMUST R&D Corporation, Los Angeles, USA.
Kang Pa LeeResearch & Development Center, UMUST R&D Corporation, Seoul, Republic of Korea.
Sang Hyun AhnDepartment. of Anatomy, College of Korean Medicine, Semyung University, Jecheon, Republic of Korea.

Funding

Ministry of Education 1345370811Ministry of Education 2021RIS-001National Research Foundation of Korea
6 · The paper itself

Abstract

purposeSarcopenia, characterized by the age-related loss of muscle mass and function, is a multifactorial condition influenced by oxidative stress, hormonal changes, and chronic inflammation. This study investigated the effects of resistance exercise and nutritional interventions, including antioxidants, such as monoterpenes, on sarcopenia prevention and treatment.

methodsTo identify relevant studies, a comprehensive literature search was conducted using electronic databases including PubMed and Google Scholar. Keywords such as "sarcopenia," "resistance exercise," "antioxidants," "nutrition," "muscle regeneration," and related terms were utilized to gather evidence on the prevention and management of sarcopenia.

resultsThis review focuses on the etiological factors of sarcopenia, particularly the decline in muscle function and acceleration of muscle protein degradation. This highlights the critical importance of the combined effects of exercise and nutrition in overcoming these challenges, with special emphasis on the potential of antioxidant intake as a promising solution for managing this condition.

conclusionAn integrated approach combining periodic resistance exercise with antioxidant-rich nutritional strategies is essential for the management of sarcopenia. By promoting muscle development and inhibiting protein breakdown, this dual strategy provides an effective framework for preventing and treating sarcopenia, and improving quality of life of the aging population. Further studies are warranted to explore the clinical potential of monoterpenes in the treatment of sarcopenia.

Indexed as

antioxidantmonoterpenesnutrientsoxidative stressresistance exercisesarcopenia

Identifiers

PMID39934634
PMCPMC11811620

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.