Evidence map›Paper›PMID 39934504›Full record

ArticleOrthopadie (Heidelberg, Germany)2025

[Nonoperative treatment for the management of osteonecrosis and bone marrow oedema of the foot and ankle].

Konstantin Horas, Annette Eidmann, Ioannis Stratos, Dominik Rak, Maximilian Rudert

Abstract readEnglish Abstract
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In one paragraph

Article in Orthopadie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Konstantin HorasOrthopädisches Zentrum für Muskuloskelettale Forschung, Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland. konstantin.horas@uni-wuerzburg.de.
Annette EidmannOrthopädische Klinik König-Ludwig-Haus, Universität Würzburg, Würzburg, Deutschland.
Ioannis StratosOrthopädische Klinik König-Ludwig-Haus, Universität Würzburg, Würzburg, Deutschland.
Dominik RakOrthopädische Klinik König-Ludwig-Haus, Universität Würzburg, Würzburg, Deutschland.
Maximilian RudertOrthopädisches Zentrum für Muskuloskelettale Forschung, Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToday, there are several nonoperative treatment measures available for the management of osteonecrosis and bone marrow oedema of the foot and ankle. TREATMENT: These include immobilisation, the use of anti-inflammatory drugs (NSAIDs), physical therapy, orthotics and extracorporeal shockwave therapy (ESWT). Furthermore, off-label use of either bisphosphonates, denosumab or prostacyclins have proven to be effective treatment options. Notably, in many cases, symptoms resolve after several months without any specific treatment. As patients often present with insufficient vitamin D levels, the measurement and correction of vitamin D status is recommended.

Indexed as

Bone Marrow DiseasesEdemaOsteonecrosisAnkleAnti-Inflammatory Agents, Non-SteroidalBone Density Conservation AgentsDenosumabDiphosphonatesExtracorporeal Shockwave TherapyFootHumansPhysical Therapy ModalitiesAnti-Inflammatory Agents, Non-SteroidalBone Density Conservation AgentsDenosumabDiphosphonatesBisphosphonatesDenosumabExtracorporeal shock wave therapyIloprostVitamin D

Identifiers

PMID39934504

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.