Evidence map›Paper›PMID 39934479›Full record

ArticleJournal of autism and developmental disorders2026

Efficacy and Safety of Propofol as a Sole Sedative for fMRI Sedation in Autism Spectrum Disorder Individuals with Low IQ.

Xiong Wei, Zhang Jiawei, Niu Maoyuan, Yu Weiyong, Chen Zhenbo, Bu Hongwei, Liu Jianjun, Liu Qi, Duan Xinyu, Bulideerqing Jiaerheng and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiong Wei *Department of Anesthesiology, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China.
Zhang Jiawei *Department of Musculoskeletal Rehabilitation, Capital Medical University Affiliated Beijing Rehabilitation Hospital, No.15, Xixiazhuang South Road, Shijingshan District, Beijing, 100144, China.
Niu MaoyuanRehabilitation Medicine School of Capital Medical University, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China.
Yu WeiyongDepartment of Medical Imaging, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China.
Chen ZhenboDepartment of Medical Imaging, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China.
Bu HongweiDepartment of Neurological Rehabilitation, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China.
Liu JianjunDepartment of Child Rehabilitation, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China.
Liu QiChangping Laboratory, Division of Brain Sciences, No.28, Kexueyuan Road, Changping District, Beijing, 102206, China.
Duan XinyuChangping Laboratory, Division of Brain Sciences, No.28, Kexueyuan Road, Changping District, Beijing, 102206, China.
Bulideerqing JiaerhengChangping Laboratory, Division of Brain Sciences, No.28, Kexueyuan Road, Changping District, Beijing, 102206, China.
Wang QiangDepartment of Anesthesiology, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China. doctor112009000105@163.com.
Zhang HaoDepartment of Neurological Rehabilitation, China Rehabilitation Research Center Beijing Boai Hospital, No.10, Jiaomen North Road, Fengtai District, Beijing, 10086, China. crrczh2020@163.com.

Funding

China Disabled Persons Federation CDPF2023KF00001
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a group of complicated neurodevelopmental disorders. Functional magnetic resonance imaging (fMRI) can help to analyze the aberrant neurological functioning in ASD. However, due to their limited cognitive abilities, ASD individuals with low IQ may face challenges in cooperating during fMRI scanning. Consequently, sedation becomes necessary for them. To analyze and evaluate the sedative efficacy and safety of a single intravenous propofol sedation regimen for ASD individuals with low IQ undergoing fMRI examination. Seventy-seven ASD individuals with low IQ, aged 4 to 23 years, who underwent fMRI examination under propofol sedation, were included. Details of the sedation protocol, evaluation indices for effectiveness such as framewise displacement (FD) and temporal signal-to-noise ratio (tSNR), as well as safety assessment measures including pulse oxygen saturation (S

Indexed as

Autism Spectrum DisorderHypnotics and SedativesMagnetic Resonance ImagingPropofolAdolescentBrainChildChild, PreschoolFemaleHumansMaleYoung AdultHypnotics and SedativesPropofolAutism spectrum disorderFunctional magnetic resonance imagingLow IQPropofolSedation

Identifiers

PMID39934479
PMCPMC13346258

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.