Trial reportScientific reports2025
Dexamethasone as an adjuvant with ropivacaine in thoracoscopy guided thoracic paravertebral block for postoperative analgesia in thoracic surgery.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of Perineural Dexamethasone on the Duration of Analgesia in Paravertebral Block: A Meta-Analysis.Journal of pain research · 2026Review
- Application and safety analysis of paravertebral block with dezocine and ropivacaine in video-assisted thoracoscopic surgery for lung cancer.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Ropivacaine for thoracoscopy-guided thoracic paravertebral block (TTPB) offers only a short duration of postoperative pain relief, which is inadequate for managing pain following thoracic surgery. Research has shown that combining dexamethasone with ropivacaine significantly prolongs the duration of analgesia from the nerve block. We hypothesised that TTPB with ropivacaine combined with dexamethasone would enhance postoperative analgesia and prolong the duration of analgesia in patients undergoing radical thoracoscopic lung cancer surgery. The study randomly assigned patients to either a control group (Group C, n = 40) or a dexamethasone group (Group D, n = 40). TTPB injection of ropivacaine or ropivacaine combined with dexamethasone prior to surgical sutures. The study compared postoperative pain satisfaction scores、48 h postoperative rescue analgesia frequency、visual analogue scale (VAS) scores, the 24-h patient-controlled analgesia (PCIA) sufentanil consumption, blood glucose levels, adverse events and recovery status. Group D demonstrated higher postoperative pain satisfaction scores and lower 48 h postoperative rescue analgesia frequency compared to Group C. Additionally, Group D had significantly lower VAS scores at 6, 12, 24, and 48 h post-operation, as well as a reduced 24-h PCIA sufentanil consumption, shorter time to first mobilization, and shorter hospital stay compared to Group C (all P < 0.05). The VAS scores at 2 h postoperatively were significantly lower in Group D compared to scores at 24 and 48 h postoperatively. Conversely, Group C showed significantly lower VAS scores at 2 h postoperatively compared to scores at 6, 12, 24, and 48 h postoperatively. The addition of dexamethasone as an adjuvant to ropivacaine enhanced the analgesic efficacy of TTPB, prolonged the duration of pain relief, and reduced the time to first ambulation and hospital stay duration.Trial Registry: ChiCTR (2400086347); Registered 28/06/2024.
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