Evidence map›Paper›PMID 39934383›Full record

ArticleScientific reports2025

Artificial intelligence support improves diagnosis accuracy in anterior segment eye diseases.

Hiroki Maehara, Yuta Ueno, Takefumi Yamaguchi, Yoshiyuki Kitaguchi, Dai Miyazaki, Ryohei Nejima, Takenori Inomata, Naoko Kato, Tai-Ichiro Chikama, Jun Ominato and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Artificial intelligence in microbial keratitis.Indian journal of ophthalmology · 2026
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hiroki MaeharaDepartment of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Yuta UenoDepartement of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8576, Japan. yu_ueno71@yahoo.co.jp.
Takefumi YamaguchiDepartment of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan.
Yoshiyuki KitaguchiDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Dai MiyazakiDivision of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, Tottori, Japan.
Ryohei NejimaDepartment of Ophthalmology, Miyata Eye Hospital, Miyazaki, Japan.
Takenori InomataDepartment of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Naoko KatoDepartment of Ophthalmology, Tsukazaki Hospital, Hyogo, Japan.
Tai-Ichiro ChikamaDivision of Ophthalmology and Visual Science, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Jun OminatoDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Tatsuya YunokiDepartment of Ophthalmology, University of Toyama, Toyama, Japan.
Kinya TsubotaDepartment of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
Masahiro OdaGraduate School of Informatics, Nagoya University, Nagoya, Japan.
Manabu SuzutaniDepartment of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Tetsuju SekiryuDepartment of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Tetsuro OshikaDepartement of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8576, Japan.

Funding

Japan Agency for Medical Research and Development Y.U. 24hma322004h0003
6 · The paper itself

Abstract

CorneAI, a deep learning model designed for diagnosing cataracts and corneal diseases, was assessed for its impact on ophthalmologists' diagnostic accuracy. In the study, 40 ophthalmologists (20 specialists and 20 residents) classified 100 images, including iPhone 13 Pro photos (50 images) and diffuser slit-lamp photos (50 images), into nine categories (normal condition, infectious keratitis, immunological keratitis, corneal scar, corneal deposit, bullous keratopathy, ocular surface tumor, cataract/intraocular lens opacity, and primary angle-closure glaucoma). The iPhone and slit-lamp images represented the same cases. After initially answering without CorneAI, the same ophthalmologists responded to the same cases with CorneAI 2-4 weeks later. With CorneAI's support, the overall accuracy of ophthalmologists increased significantly from 79.2 to 88.8% (P < 0.001). Specialists' accuracy rose from 82.8 to 90.0%, and residents' from 75.6 to 86.2% (P < 0.001). Smartphone image accuracy improved from 78.7 to 85.5% and slit-lamp image accuracy from 81.2 to 90.6% (both, P < 0.001). In this study, CorneAI's own accuracy was 86%, but its support enhanced ophthalmologists' accuracy beyond the CorneAI's baseline. This study demonstrated that CorneAI, despite being trained on diffuser slit-lamp images, effectively improved diagnostic accuracy, even with smartphone images.

Indexed as

Anterior Eye SegmentArtificial IntelligenceEye DiseasesCataractDeep LearningFemaleHumansMaleOphthalmologistsSmartphoneAI supportArtificial intelligenceOcular surfaceSlit-lamp imageSmartphone image

Identifiers

PMID39934383
PMCPMC11814138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.