Evidence map›Paper›PMID 39934272›Full record

ArticleScientific reports2025

Evolution of pathogenic Escherichia coli harboring the transmissible locus of stress tolerance: from food sources to clinical environments.

Maxsueli Machado, Pedro Panzenhagen, Flávia Figueira Aburjaile, Bertram Brenig, Mateus Matiuzzi da Costa, Vasco Ariston de Carvalho Azevedo, Eduardo Eustáquio de Souza Figueiredo, Carlos Adam Conte-Junior

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maxsueli MachadoFood Science Program (PPGCAL), Chemistry Institute (IQ), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, 21941-909, Brazil.ORCID 0000-0002-0189-9017
Pedro PanzenhagenCenter for Food Analysis (NAL), Technological Development Support Laboratory (LADETEC), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-7287-2663
Flávia Figueira AburjaileLaboratory of Integrative Bioinformatics, Preventive Veterinary Medicine Department, Veterinary School, Federal University of Minas Gerais, Belo Horizonte, 31270- 901, Minas Gerais, Brazil.ORCID 0000-0002-1067-1882
Bertram BrenigGeorg-August-Universität Göttingen, Göttingen, Germany.ORCID 0000-0002-7635-9656
Mateus Matiuzzi da CostaAnimal Science Program, Federal University of Vale do São Francisco (UNIVASF), Pernambuco, 56300-000, Brazil.ORCID 0000-0002-9884-2112
Vasco Ariston de Carvalho AzevedoLaboratory of Integrative Bioinformatics, Preventive Veterinary Medicine Department, Veterinary School, Federal University of Minas Gerais, Belo Horizonte, 31270- 901, Minas Gerais, Brazil.ORCID 0000-0002-4775-2280
Eduardo Eustáquio de Souza FigueiredoAnimal Science Program (PPGCA), Federal University of Mato Grosso (UFMT), Cuiabá, 78060-900, Mato Grosso, Brazil.ORCID 0000-0002-2608-4324
Carlos Adam Conte-JuniorFood Science Program (PPGCAL), Chemistry Institute (IQ), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, 21941-909, Brazil. conte@iq.ufrj.br.ORCID 0000-0001-6133-5080

Funding

Conselho Nacional de Desevolvimento Científico e Tecnólogico- CNPq/Brazil 140016/2021-0Conselho Nacional de Desevolvimento Científico e Tecnólogico- CNPq/Brazil 310181/2021-6Conselho Nacional de Desevolvimento Científico e Tecnólogico- CNPq/Brazil 313119/2020-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.999872/2024-00Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro - FAPERJ/Brazil E-26/201.638/2024Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro - FAPERJ/Brazil E-26/204.145/2022
6 · The paper itself

Abstract

Escherichia coli (E. coli) carrying the transmissible locus of stress tolerance (tLST) are able to overcome numerous environmental challenges. In our in-silico study, we aimed to characterize tLST in terms of its variants in 793 genomes of E. coli from Brazil originating from food, environmental and clinical (animal and human) sources, and to perform a temporal analysis in order to identify the historical moment of its emergence. We also analyzed the presence of two Yersinia high pathogenicity island (HPI) variants in E. coli genomes, describing other genes and accessory for resistance, persistence, mobile elements (plasmids) and sequence types. The prevalence of the tLST was 10% in E. coli from Brazil, predominantly observed in milk-originating genomes, within the prevalent tLST

Indexed as

Escherichia coliEscherichia coli InfectionsEvolution, MolecularStress, PhysiologicalAnimalsBrazilFood MicrobiologyGenome, BacterialGenomic IslandsHumansMilkVirulenceVirulence FactorsVirulence FactorsAntimicrobial resistance genesE. coliHigh-pathogenicity islandLocus of heat resistanceVirulence genes

Identifiers

PMID39934272
PMCPMC11814101

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.