Observational studyHeart (British Cardiac Society)2025
Impact of prognostic nutritional index on mortality among patients receiving coronary artery bypass grafting surgery: a retrospective cohort study.
Observational study in Heart (British Cardiac Society), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- The merits of the prognostic nutritional index and neutrophil-to-lymphocyte ratio in predicting outcomes of coronary artery bypass grafting: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Article
- Prognostic nutritional index and long-term outcomes after coronary artery bypass grafting.BMC surgery · 2026Article
- Relationship Between Prognostic Nutritional Index and Stroke-Associated Pneumonia in Elderly Patients: A Two-Center Study of Spontaneous Intracerebral Hemorrhage.Food science & nutrition · 2026Article
- Association of the prognostic nutritional index and geriatric nutritional risk index with clinical outcomes in patients undergoing coronary artery bypass surgery: a systematic review and meta-analysis.Journal of thoracic disease · 2026Article
- The Critical Role of Nutritional and Procedural Factors in CTO-PCI Patient Prognosis.Life (Basel, Switzerland) · 2026Article
- Predicting 90-Day Mortality After Geriatric Hip Fracture Using Combined Preoperative and Perioperative Risk Factors.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Association between prognostic nutritional index and 28-day mortality in patients with sepsis-associated acute respiratory distress syndrome.Frontiers in nutrition · 2026Article
- Evaluating objective nutritional biomarkers for the prediction of sarcopenia in Crohn's disease: development and internal validation of a clinical nomogram.Frontiers in nutrition · 2026Article
- Association between PNI and all-cause mortality in ischemic stroke patients: a large-scale retrospective cohort study.Frontiers in nutrition · 2026Article
- Association between prognostic nutritional index and prognosis of patients receiving coronary artery bypass grafting surgery: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Review
- Low prognostic nutritional index is highly associated with periprosthetic joint infection in revision arthroplasty: a 14-year retrospective cohort study.Journal of orthopaedic surgery and research · 2025Article
- Long-Term Prognostic Value of the Prognostic Nutritional Index in Patients Undergoing Coronary Artery Bypass Grafting.Journal of the American Heart Association · 2025Article
- Article
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14 authors.
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Abstract
backgroundThe Prognostic Nutritional Index (PNI), calculated from serum albumin levels and lymphocyte counts, is a simple and objective measure of nutritional status. While PNI has been shown to be a significant prognostic tool in gastrointestinal surgery and heart failure, its role in patients undergoing coronary artery bypass grafting (CABG) remains unclear. This study aims to evaluate whether PNI can serve as a meaningful risk factor for patients undergoing CABG.
methodsThis observational retrospective analysis involved a substantial sample of 2889 patients who underwent isolated CABG at one of four medical centres. The primary outcomes included short- and long-term mortality. Perioperative serum albumin levels and total lymphocyte counts used to calculate PNIs were collected 48 hours before the operation, 24 hours after the operation and at discharge. Univariate and multivariate logistic regression analyses were conducted to identify the risk factors of short-term mortality. Survival and relative risks were assessed using Cox regression analysis and the Kaplan-Meier test.
resultsAmong the 2889 patients, 64 (2.2%) died within 30 days following CABG. Multivariate logistic regression revealed that higher preoperative PNI was independently associated with reduced short-term mortality (OR=0.852 per unit increase, 95% CI 0.802 to 0.904, p<0.001). Regarding long-term outcomes, among the 2825 patients who were discharged alive, 199 deaths occurred over a median follow-up period of 54.9 months. Patients with a normal PNI at discharge (>40) exhibited significantly higher long-term survival rates compared with those with a lower PNI (≤40) (log-rank p=0.003). Multivariate Cox regression analysis confirmed that a normal PNI at discharge(>40) independently predicted a lower risk of long-term all-cause mortality (HR=0.718, 95% CI 0.529 to 0.974, p=0.033).
conclusionsPNI at various time points may play a crucial predictive role in mortality among CABG-treated patients, and a low PNI serves as a risk factor for both short- and long-term survival.
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