SynthesisJournal of thrombosis and haemostasis : JTH2025
Criteria for home treatment of patients with acute pulmonary embolism (the Emergency Advisory and Research international board on Thrombosis and Hemostasis EARTH - rule): an international Delphi consensus study.
Synthesis in Journal of thrombosis and haemostasis : JTH, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Safety of outpatient management of pulmonary embolism diagnosed in the emergency department.CJEM · 2026Article
- Contemporary Challenges in Venous Thromboembolism: Evolving Populations and Implications for Management and Risk Stratification.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The safety of home treatment for patients with low-risk acute pulmonary embolism (PE) has been confirmed in several studies; however, these studies have used varying triaging criteria and outcomes, leading to inconsistencies in defining safe discharge parameters. This study aimed to identify adverse outcomes that make home discharge inappropriate, as well as their timeframe and clinical criteria, indicating high risk for such events. Following a systematic literature review, an international expert panel participated in 3 Delphi survey rounds. Experts evaluated each proposal using a Likert scale, and consensus required 75% agreement. Items without consensus were reassessed in subsequent rounds until agreement was achieved. Of the 55 invited experts, 38 from 13 countries participated (69%). Consensus was reached on 6 adverse events for a composite outcome, with a 7-day postdischarge timeframe and a maximum acceptable incidence of 2.0%. The panel defined a triaging rule with 14 clinical criteria as contraindications for home treatment, grouped into 4 categories: hemodynamic (3), respiratory (1), hemorrhagic (7), and medico-social (3). An extended rule, adding 3 optional biological or imaging criteria, was developed to further refine risk assessment. The expert panel established a consensus-based triaging rule for the home treatment of PE patients. This framework defines adverse outcomes, a 7-day safety timeframe, and an acceptable risk threshold for assessing patient safety. Future prospective studies are needed to validate the Emergency Advisory and Research international board on Thrombosis and Hemostasis rule before its implementation in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.