Evidence map›Paper›PMID 39933076›Full record

ArticleJournal of the American Chemical Society2025

Animal-Encoded Nonribosomal Pathway to Bursatellin Analogs.

Aarthi Venugopalan, Eric W Schmidt

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. An Alkaloid Biosynthetic Gene Bundle in Animals.Journal of the American Chemical Society · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Aarthi VenugopalanDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
Eric W SchmidtDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0001-5839-694X

Funding

Symbiosis and Chemical Diversity GenerationR35GM148283 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Eric W Schmidt · 2023 to 2026
$2.2M
NIGMS NIH HHS R35 GM148283
6 · The paper itself

Abstract

The bursatellin-oxazinin family is a series of tyrosine-derived, nitrile-containing marine natural products from gastropod and bivalve molluscs. Although the first analogs were identified and associated with toxicity 40 years ago, their biosynthetic origins were unknown. During an investigation of published mollusc genomes and transcriptomes, we serendipitously identified a putative bursatellin biosynthetic gene cluster (referred hereafter as the

Indexed as

Peptide SynthasesAnimalsMolluscaMultigene Familynon-ribosomal peptide synthasePeptide Synthases

Identifiers

PMID39933076
PMCPMC11869996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.