Evidence map›Paper›PMID 39932768›Full record

ArticleJMIR research protocols2025

Effectiveness of Anti-Gravity Treadmill Exercise After Total Knee Arthroplasty: Protocol for a Randomized Controlled Trial.

Elina Jääskeläinen, Mikko Manninen, Heikki Hurri, Mikko Rantasalo, Yun Zhou, Hannu Kautiainen, Leena Ristolainen

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03904030 (Postoperative Rehabilitation After Knee Arthroplasty, With or Without Anti-Gravity Treadmill), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03904030 nacompletednot on this map

Postoperative Rehabilitation After Knee Arthroplasty, With or Without Anti-Gravity Treadmill

TypeinterventionalSponsorOrton Orthopaedic HospitalRan2019 to 2022Enrolled62ConditionsRehabilitationArmsRehabilitation with or without Anti-Gravity Treadmill
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elina JääskeläinenLaurea University of Applied Sciences, Espoo, Finland.ORCID 0009-0001-6043-7357
Mikko ManninenOrton Orthopaedic Hospital, Helsinki, Finland.ORCID 0000-0002-9681-8821
Heikki HurriResearch Institute Orton, Helsinki, Finland.ORCID 0000-0002-1672-6960
Mikko RantasaloOrton Orthopaedic Hospital, Helsinki, Finland.ORCID 0000-0002-9688-209X
Yun ZhouOrton Orthopaedic Hospital, Helsinki, Finland.ORCID 0009-0000-1768-4507
Hannu KautiainenPrimary Health Care Unit, Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0003-0786-0858
Leena RistolainenResearch Institute Orton, Helsinki, Finland.ORCID 0000-0002-3041-260X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative rehabilitation following total knee arthroplasty (TKA) varies worldwide. In Finland, patients receive guidance on safe walking and home exercises from a physiotherapist both before and after TKA. These are performed independently after surgery. However, a sedentary lifestyle is rather common among patients who have undergone TKA, with pain often limiting postoperative walking, training, and activities of daily living.

objectiveThis randomized controlled trial aimed to investigate the effectiveness of anti-gravity exercise, precisely the AlterG anti-gravity treadmill, on postoperative rehabilitation following TKA and to obtain new knowledge on this form of rehabilitation to better use it in the future.

methodsThis randomized controlled trial study divided the patients into two groups: the intervention group and the control group. The follow-up period was 12 months. Research data were collected through questionnaires and functional tests. All patients in both groups responded to the questionnaires and participated in functional tests before surgery as well as 4 and 12 months after surgery. Patients in the intervention group exercised on the AlterG treadmill 10 times after the surgery. All the patients in this study performed the exercises as instructed when they were in the hospital. The primary outcomes were perceived pain, walking ability, and quality of life.

resultsThe data collection process began in 2018 and concluded in 2022, intending to obtain valuable information regarding the effect of AlterG training after TKA and determine whether it, along with traditional exercises, could be an effective form of rehabilitation that can be performed at home. We hypothesized that AlterG training would lead to faster rehabilitation, better walking quality, improved quality of life, improved physical activity, and improved overall functioning. The results of this study will be analyzed in 2025 and 2026.

conclusionsThis study provides information on how AlterG training can be used in rehabilitation after TKA, further enhancing the rehabilitation program for patients undergoing TKA in general.

trial registrationClinicalTrials.gov NCT03904030; https://clinicaltrials.gov/study/NCT03904030. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/59935.

Indexed as

Arthroplasty, Replacement, KneeExercise TherapyActivities of Daily LivingAgedFemaleFinlandHumansMaleMiddle AgedQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeWalkingAlterGanti-gravity treadmillpainpostoperative rehabilitationquality of lifetotal knee arthroplastywalking ability

Identifiers

PMID39932768
PMCPMC11862769

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.