Evidence map›Paper›PMID 39932600›Full record

ArticleJournal of neurology2025

Global burden of central nervous system tumors and cancers in older adults: the global burden of disease study 2021.

Peng Liu, Lunxin Liu, Xiaoyin Liu, Gaowei Li, Liangxue Zhou

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Article in Journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Peng LiuDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, Sichuan, China.
Lunxin LiuDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, Sichuan, China.
Xiaoyin LiuDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, Sichuan, China.
Gaowei LiDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, Sichuan, China.
Liangxue ZhouDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, Sichuan, China. westchina2021@163.com.

Funding

Major Scientific and Technological Achievements Transformation Project of Ningxia Hui Autonomous Region 2022CJE09013National Natural Science Foundation of China 82401629National Natural Science Foundation of China 82473334
6 · The paper itself

Abstract

backgroundThis study aims to elucidate and predict the global disease burden and trends associated with central nervous system (CNS) tumors and cancers among older patients.

methodsData from the Global Burden of Disease 2021 database were used to calculate the age-standardized incidence rate (ASIR), prevalence rate (ASPR), death rate (ASDR), disability-adjusted life-years (DALYs), and the average annual percentage change (AAPC) to assess burden and trends from 1990 to 2021. A Bayesian age-period-cohort model was applied to project the global burden of CNS tumors and cancers in older patients over the next 30 years.

resultsThe ASIR among older adults worldwide increased by 3.59 cases per 100,000 population from 1990 to 2021, with an AAPC of 0.86%. The ASPR rose by 9.83 cases per 100,000 people, with an AAPC of 1.57%. The ASDR increased from 10.99 per 100,000 people to 13.01 per 100,000 people. DALYs also rose continuously from 234.21 per 10,000 population to 265.1, with an AAPC of 0.4%. It is anticipated that from 2021 to 2051, the ASIR, ASDR, and age-standardized DALYs will exhibit a declining pattern; however, the ASPR will initially experience a slight decrease before gradually rising again.

conclusionsThe global burden has significantly increased from 1990 to 2021. Projections indicate that over the next 30 years, the total number of patients will rise, while the age-standardized rates will show a slow downward trend.

Indexed as

Central Nervous System NeoplasmsGlobal Burden of DiseaseGlobal HealthNeoplasmsAgedAged, 80 and overDisability-Adjusted Life YearsFemaleHumansIncidenceMaleMiddle AgedPrevalenceBayesian Age-period-cohort analysisCNS tumors and cancersGlobal burden of diseaseOlder adults

Identifiers

PMID39932600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.