Evidence map›Paper›PMID 39932538›Full record

ReviewUrolithiasis2025

Advances in the mechanism of urinary proteins in calcium oxalate kidney stone formation.

Mingcheng Shi, Xiaozhe Su, Heng Xiang, Qianlin Song, Sixing Yang

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Urolithiasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Clinical features ofFrontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Mingcheng Shi *Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People's Republic of China.
Xiaozhe Su *Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People's Republic of China.
Heng Xiang *Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People's Republic of China.
Qianlin SongDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People's Republic of China. qlsong@whu.edu.cn.
Sixing YangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People's Republic of China. sxyang@whu.edu.cn.

Funding

National Natural Science Foundation of China 82270797
6 · The paper itself

Abstract

Kidney stones are a common urological disease worldwide, imposing a significant burden on healthcare systems. Calcium oxalate stones are the predominant form of urinary calculi, with two main theoretical models explaining their pathogenesis: the fixed particle and free particle models. Regardless of the model, the formation of calcium oxalate kidney stones is inseparably linked to crystal nucleation, growth, aggregation, and adhesion in urine. Growing evidence highlights the significant role of urinary proteins, particularly matrix proteins, in the development of calcium oxalate stones. The review classifies urinary proteins impacting calcium oxalate stone formation into three groups: inhibitors, promoters, and dual-regulators, outlining their contributions to the formation process.

Indexed as

Calcium OxalateKidney CalculiCrystallizationExtracellular Matrix ProteinsHumansCalcium OxalateExtracellular Matrix ProteinsCalcium oxalate stonesCrystalKidney stonesMatrix proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.