Evidence map›Paper›PMID 39932435›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

GhLPF1 Associated Network Is Involved with Cotton Lint Percentage Regulation Revealed by the Integrative Analysis of Spatial Transcriptome.

Hongyu Wu, Luyao Wang, Shengjun Zhao, Mengtao Gao, Junfeng Cao, Yupeng Hao, Li Yu, Ting Zhao, Siyuan Wang, Jin Han and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Relief of GbDEAH12Nature communications · 2026
    Article
  2. Article
  3. Genome-Wide Comparative Analysis of Invertases in theCurrent issues in molecular biology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hongyu WuZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Luyao WangYazhou Bay Science and Technology City, Hainan Institute of Zhejiang University, Building 11, Yongyou Industrial Park, Yazhou District, Sanya, Hainan, 572025, China.
Shengjun ZhaoZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Mengtao GaoNational Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, 210095, China.
Junfeng CaoSchool of Life Sciences, Centre for Cell & Developmental Biology and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Shatin, Hong Kong, 999077, China.
Yupeng HaoZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Li YuZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Ting ZhaoZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Siyuan WangZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Jin HanZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Yumeng ZhuZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Yongyan ZhaoZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Jie LiNational Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, 210095, China.
Ke NieZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Kening LuNational Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, 210095, China.
Linyun DingNational Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, 210095, China.
Zhiyuan ZhangYazhou Bay Science and Technology City, Hainan Institute of Zhejiang University, Building 11, Yongyou Industrial Park, Yazhou District, Sanya, Hainan, 572025, China.
Tianzhen ZhangZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.
Xueying GuanZhejiang Provincial Key Laboratory of Crop Genetic Resources, Institute of Crop Science, Plant Precision Breeding Academy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 300058, China.ORCID https://orcid.org/0000-0002-6528-2518

Funding

Finance science and technology project of Xinjiang Uyghur Autonomous Region 2023A01JCIC-MCP, Bureau of Science Technology Industry and Information Technology of Sanya 2022KJCX88National Key Research and Development Program 2022YFF1001400National Natural Science Foundation of China 32260179Ph.D. Scientific Research and Innovation Foundation of Sanya Yazhou Bay Science and Technology City HSPHDSRF-2022-04-009Research Fund for Researchers, Hainan Institute of Zhejiang University 0202-6602-A12202
6 · The paper itself

Abstract

Cotton fibers, derived from the epidermis of the ovule, provide a sustainable natural fiber source for the textile industry. Traits related to fiber yield are predominantly determined by molecular regulations in the epidermis of the outer integument (OI) region of the cotton ovule. Here, we identify an R2R3 MYB transcription factor coding gene GhLPF1 within the QTL-LP-ChrA06 locus for lint percentage (LP, percentage of lint to seed cotton) through constructing the 1-Day Post Anthesis Cotton Ovule Spatial Transcriptome Atlas. GhLPF1 is subjected as a downstream target of miR828 during fiber development. The direct downstream genes (DDGs) of GhLPF1 are biased to increased expression in GhLPF1-CR, and are preferentially expressed in OI, so that GhLPF1 is primarily a transcriptional repressor to its DDGs. Population-wide transcriptome analysis confirms that expression variation of GhLPF1-DDGs is significantly biased to negative correlation with LP, among which a type I homeobox protein-coding gene GhHB6 is further validated to be the directly downstream gene of GhLPF1. Given these data, it is demonstrated that GhLPF1 mediates a regulation network in LP as a transcriptional repressor, which makes it a valuable functional marker for fiber-trait improvement application from QTL-LP-ChrA06.

Indexed as

Gene Expression Regulation, PlantGossypiumPlant ProteinsTranscription FactorsTranscriptomeCotton FiberGene Expression ProfilingOvuleQuantitative Trait LociPlant ProteinsTranscription Factorsfiber regulationpopulation‐wide transcriptome analysispost‐transcriptional regulationspatial transcriptome

Identifiers

PMID39932435
PMCPMC11967919

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.