Evidence map›Paper›PMID 39932304›Full record

ArticleThe Journal of international medical research2025

Effects of 0.01 mM strontium on human periodontal ligament stem cell osteogenic differentiation via the Wnt/

Tongke Sun, Dan Ma, Yang Song, Jing Hu, Ziqing Yang, Xu Wang, Jun Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Harnessing strontium in regenerative dentistry: progress and perspectives.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tongke SunShandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.ORCID 0009-0008-1725-0563
Dan MaDepartment of Stomatology & Shandong, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China.
Yang SongShandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Jing HuShandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Ziqing YangShandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Xu WangShandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Jun ZhangShandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStrontium (Sr

methodshPDLSCs were harvested from extracted premolars and characterized by flow cytometry, then cultured and treated with various Sr

resultsThe hPDLSCs were successfully isolated and cultured

conclusionsSr

Indexed as

Cell DifferentiationOsteogenesisPeriodontal LigamentStem CellsStrontiumWnt Signaling PathwayAlkaline Phosphatasebeta CateninCell ProliferationCells, CulturedCore Binding Factor Alpha 1 SubunitHeterocyclic Compounds, 3-RingHumansAlkaline Phosphatasebeta CateninCore Binding Factor Alpha 1 SubunitHeterocyclic Compounds, 3-RingStrontiumXAV939cell proliferationdifferentiationHuman periodontal ligament stem cellosteogenesisperiodontitisstrontiumWnt/β-catenin signaling

Identifiers

PMID39932304
PMCPMC11815949

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.