Evidence map›Paper›PMID 39932299›Full record

ArticleApplied and environmental microbiology2025

Branched-chain amino acid metabolism supports Roseobacteraceae positive interactions in marine biofilms.

Han Cui, Shuaitao Wang, Shen Fan, Hongan Long, Jinshui Lin, Wei Ding, Weipeng Zhang

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Genomic and transcriptomic insights intoMicrobiology (Reading, England) · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Han Cui *MOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Shuaitao Wang *MOE Key Laboratory of Marine Genetics and Breeding and College of Marine Life Sciences, Ocean University of China, Qingdao, China.ORCID 0009-0003-6752-4968
Shen FanMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Hongan LongMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.
Jinshui LinCollege of Life Sciences, Yan'an University, Yan'an, China.ORCID 0000-0001-5714-7917
Wei DingMOE Key Laboratory of Marine Genetics and Breeding and College of Marine Life Sciences, Ocean University of China, Qingdao, China.ORCID 0000-0002-1847-244X
Weipeng ZhangMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, China.ORCID 0000-0002-1231-8927

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interspecies interactions are key factors affecting the stability of microbial communities. However, microbial interactions in marine biofilms, which constitute up to 80% of the microbial biomass in certain marine environments, are not well understood. We addressed this knowledge gap by coculturing four marine biofilm-derived Roseobacteraceae strains ( IMPORTANCE: Interspecies interactions are crucial for microbial community structure and function. Despite well-studied social behaviors in model microorganisms, species interactions in natural marine biofilms especially Roseobacteraceae with complex metabolic pathways are not well understood. Our findings suggest that positive microbial interactions, which can be mediated by branched-chain amino acid biosynthesis, are common among marine-biofilm Roseobacteraceae. This study provides new insights into microbial interactions and the ecology of marine biofilms.

Indexed as

Amino Acids, Branched-ChainBiofilmsMicrobial InteractionsRhodobacteraceaeSeawaterAmino Acids, Branched-Chainbranched-chain amino acidsinterspecies interactionmarine biofilmRoseobacteraceae

Identifiers

PMID39932299
PMCPMC11921356

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.