Evidence map›Paper›PMID 39932292›Full record

ArticleMicrobiology spectrum2025

Clinical performance of Abbott ID NOW™ COVID-19 2.0 rapid molecular point-of-care test compared to three real-time RT-PCR assays.

Maria D Iglesias-Ussel, Aleah Bowie, Jack G Anderson, Yin Li, Lawrence P Park, Jose F Cardona, Patrick Dennis, Valentine Ebuh, Steven A Geller, Manish Jain and 8 more

Abstract readComparative Study
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maria D Iglesias-UsselDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-3679-9681
Aleah BowieDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Jack G AndersonDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Yin LiAbbott Rapid Diagnostics, a Division of Abbott Laboratories, San Diego, California, USA.
Lawrence P ParkDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Jose F CardonaIndago Research and Health Center Inc, Hialeah, Florida, USA.
Patrick DennisDelRicht Research, New Orleans, Louisiana, USA.
Valentine EbuhGlobal Medical Research LLC, Dallas, Texas, USA.
Steven A GellerCentennial Medical Group, Elkridge, Maryland, USA.
Manish JainGreat Lakes Clinical Trials, Chicago, Illinois, USA.
Mark M McKenzieWR - ClinSearch, LLC, Chattanooga, Tennessee, USA.
Kian Merchant-BornaDepartment of Emergency Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Anand PatelConquest Research LLC, Winter Park, Florida, USA.
Amy SiegelMediSync Clinical Research LLC, Austin, Texas, USA.
Guy S StraussMulti-Specialty Research Associates Inc, Lake City, Florida, USA.
Joby J ThoppilDepartment of Emergency Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Aaron S WeinbergCarbon Health Technologies Inc.& Carbon Health Medical Group, Oakland, California, USA.
Christopher W WoodsDivision of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Timely diagnosis of SARS-CoV-2 is important for infection control and treatment. Real-time reverse transcriptase PCR (rRT-PCR) tests are the reference standard for diagnosis but often require a centralized laboratory, making them time-intensive and unsuitable for resource-limited settings. The Abbott ID NOW™ COVID-19 2.0 assay is a rapid point-of-care (POC), isothermal molecular test for qualitative detection of SARS-CoV-2. We prospectively evaluated its clinical performance against three reference rRT-PCR tests: Hologic Panther Fusion, Roche Cobas, and CDC 2019-nCoV RT-PCR Diagnostic Panel. Investigators enrolled 3,530 subjects, with 3,146 evaluable. In symptomatic subjects ( IMPORTANCE: The Abbott ID NOW

Indexed as

COVID-19COVID-19 Nucleic Acid TestingMolecular Diagnostic TechniquesPoint-of-Care TestingReal-Time Polymerase Chain ReactionSARS-CoV-2AdolescentAdultAgedAged, 80 and overChildCOVID-19 TestingFemaleHumansMaleMiddle AgedCOVID-19ID NOWisothermalnicking endonuclease amplification reaction (NEAR)POCrapid testingrRT-PCRSARS-CoV-2

Identifiers

PMID39932292
PMCPMC11877999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.