Evidence map›Paper›PMID 39932281›Full record

ArticleMicrobiology spectrum2025

Tp40: a new potential prognostic and diagnostic marker for syphilis.

Jiangchen Yao, Bibo Xie, Xuan Ding, Han Yu, Ting Lin, Junxia Duan, Xiaohong Zhang, Peng Ling, Feijun Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiangchen Yao *MOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.
Bibo Xie *MOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.
Xuan DingMOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.
Han YuMOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.
Ting LinMOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.
Junxia DuanDepartment of Clinical Laboratory Medicine, The Central Hospital of Shaoyang, Shaoyang City, China.
Xiaohong ZhangMOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.
Peng LingDepartment of Critical Care Medicine, The Central Hospital of Shaoyang, Shaoyang City, China.
Feijun ZhaoMOE Key Lab of Rare Pediatric Diseases&Institute of Pathogenic Biology and Key Laboratory of Special Pathogen Prevention and Control of Hunan Province, Hengyang Medical College, University of South China, Hengyang, China.ORCID 0000-0001-9542-6896

Funding

Health High-Level Talents Major Scientific Research Project of Hunan Provincial Health Commission R2023004Health Research Key Project of Hunan Provincial Health Commission no. 20221064723Hunan Province Natural Science Foundation no. 2023JJ30530,no. 2024JJ5343Science and Technology Planning Project of Shaoyang City 2023GZ4043
6 · The paper itself

Abstract

The characterization of IMPORTANCE: In recent years, syphilis, as a chronic infectious disease, has once again attracted much attention.

Indexed as

Antigens, BacterialBacterial ProteinsSyphilisTreponema pallidumAdultAnimalsAntibodies, BacterialBiomarkersDisease Models, AnimalEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiceMiddle AgedPrognosisAntibodies, BacterialAntigens, BacterialBacterial ProteinsBiomarkersinfection phase-dependent antigenprotein characterizationserodiagnosisTp40Treponema pallidum

Identifiers

PMID39932281
PMCPMC11878081

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.