ArticleMovement disorders clinical practice2025
Assessing Eligibility for Apomorphine Therapy in Parkinson's Disease: The Telemonitoring Potential.
Article in Movement disorders clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial: Digital biomarkers in movement disorders.Frontiers in neurology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundAlthough there are established guidelines for the selection of suitable candidates, objective and timely referral for the use of apomorphine remains challenging.
objectivesThis research examined how telemonitoring may facilitate referrals for continuous subcutaneous apomorphine infusion in Parkinson's disease (PD).
methodsA Blind Rater and a multi-disciplinary team (MDT) including an expert PD nurse, neurologist, and geriatrician determined apomorphine pump treatment eligibility for 20 patients with PD. The MDT considered telemonitoring data and physical examination to determine eligibility. The Blind Rater used only telemonitoring data (PDMonitor®) to evaluate eligibility.
resultsThe results show that using wearable sensors to determine appropriateness of apomorphine pump treatment is similar to a complete method that combines objective motor symptom monitoring with clinical evaluation. The MDT and blind rater had a 0.89 Cohen's kappa coefficient, which suggests high rate of agreement. The best-performing objective metric for differentiating patients who were recommended (APO) from those non-recommended (non-APO) for apomorphine pump therapy, was the device-reported percentage of time in the "ON" state, which takes into consideration the "OFF" and dyskinesia time. The APO group had lower values in this metric and could be differentiated from the non-APO group accurately (85%).
conclusionsUsing telemonitoring to determine eligibility for apomorphine therapy might improve evaluation and treatment in patients with PD and, therefore help improve their quality of life.
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