Evidence map›Paper›PMID 39931683›Full record

ArticleBeilstein journal of organic chemistry2025

Three-component reactions of conjugated dienes, CH acids and formaldehyde under diffusion mixing conditions.

Dmitry E Shybanov, Maxim E Kukushkin, Eugene V Babaev, Nikolai V Zyk, Elena K Beloglazkina

Abstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dmitry E ShybanovDepartment of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Maxim E KukushkinDepartment of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Eugene V BabaevDepartment of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Nikolai V ZykDepartment of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.
Elena K BeloglazkinaDepartment of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0001-6796-8241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A diffusion mixing technique with a volatile reagent was successfully used to generate crotonic condensation adducts of active methylene compounds and formaldehyde at room temperature in the absence of strong acids and bases. The formed adducts were highly reactive intermediates capable of reacting with dienes in a three-component reaction, leading to the formation of Diels-Alder main reaction products.

Indexed as

[4 + 2]-cycloadditionaldol condensationdiffusion mixingformaldehydeKnoevenagel condensationthree-component reactions

Identifiers

PMID39931683
PMCPMC11809574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.