Evidence map›Paper›PMID 39931658›Full record

Trial reportF1000Research2022

Effectiveness and safety profile of mesenchymal stem cell secretome as a treatment for severe cases of COVID-19: a randomized controlled trial.

Murdani Abdullah, Jeanne Adiwinata Pawitan, Cosphiadi Irawan, Rahyussalim Jabir, Dita Aditianingsih, Isabella Kurnia Liem, Robert Sinto, Adityo Susilo, Mira Yulianti, Raden Rara Diah Handayani and 7 more

Abstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in F1000Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Murdani AbdullahDivision of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia.ORCID 0000-0002-8801-0283
Jeanne Adiwinata PawitanDepartement of Histology, University of Indonesia, Jakarta, Indonesia.ORCID 0000-0002-6551-5238
Cosphiadi IrawanDivision of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia.
Rahyussalim JabirDepartment of Orthopaedic and Traumatology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia.
Dita AditianingsihDepartment of Anesthesiology and Intensive Care, University of Indonesia, Jakarta, 10430, Indonesia.
Isabella Kurnia LiemStem Cell Medical Technology Integrated Service Unit, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia.
Robert SintoDivision of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, University of Indonesia,Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Adityo SusiloDivision of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, University of Indonesia,Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Mira YuliantiDivision of Pulmonology, Departement of Internal Medicine, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Raden Rara Diah HandayaniDepartment of Pulmonology and Respiratory Medicine, Universitas Indonesia Hospital, Jakarta, Indonesia.
Irandi Putra PratomoDepartment of Pulmonology and Respiratory Medicine, Universitas Indonesia Hospital, Jakarta, Indonesia.ORCID 0000-0003-0826-3967
Erlina BurhanDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta, 10430, Indonesia.ORCID 0000-0002-8115-8293
Triya DamayantiDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta, 10430, Indonesia.ORCID 0000-0002-3779-4372
Heri WibowoIntegrated Laboratory, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Ismail Hadisoebroto DilogoStem Cell Medical Technology Integrated Service Unit, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia.ORCID 0000-0002-6202-0918
Hary Sakti MuliawanDepartment of Department of Cardiology and Vascular Medicine, Universitas Indonesia Hospital, Depok, Indonesia.
Mia ElhidsiDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia - Persahabatan Hospital, Jakarta, 10430, Indonesia.ORCID 0000-0002-5005-044X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Mesenchymal Stem CellsSARS-CoV-2AdultCytokinesDouble-Blind MethodFemaleHumansInterleukin-6MaleMesenchymal Stem Cell TransplantationMiddle AgedSeverity of Illness IndexTreatment OutcomeCytokinesInterleukin-6COVID-19cytokineinflammation mediatorsmesenchymal stem cellsecretome

Identifiers

PMID39931658
PMCPMC11809480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.