ArticleCureus2025
Herpes Simplex Esophagitis in an Immunocompetent Adult.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Herpes simplex virus esophagitis in immunocompetent patients: a case report and updated literature review.International journal of surgery case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herpes simplex esophagitis (HSE) caused by herpes simplex virus (HSV) infection is a well-recognized opportunistic infection in an immunocompromised host. HSE in immunocompetent patients is an uncommon clinical event; however, when it does occur, it is generally a self-limiting condition. This case involves an immunocompetent 19-year-old female patient who presented to the emergency department (ED) with a three-day history of nausea, vomiting, and inability to tolerate oral intake. The diagnosis of HSE was made via histopathological analysis and HSV-1 polymerase chain reaction (PCR) of an esophageal biopsy. The patient clinically improved on acyclovir. HSE in the immunocompetent patient is a rare clinical entity. A combination of history, upper endoscopy, histopathology, and HSV-PCR is used to diagnose HSE. Antiviral therapy with acyclovir may reduce the severity and duration of infection.
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Registered trials
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