Evidence map›Paper›PMID 39931444›Full record

ArticleChina CDC weekly2025

Multicenter Study on the Prevalence of Human Respiratory Syncytial Virus Coinfection and Disease Burden Among Hospitalized Children Aged 5 Years and Younger - 5 Prefecture-level Cities, Zhejiang Province, China, 2018-2023.

Wanwan Sun, An Zhu, Zhiyong Zhu, Jinren Pan, Chaorong Ni, Wenjie Wu, An Tang, Lei Guo, Zhao Yu, Xicheng Gu and 4 more

Abstract read
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wanwan SunDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, China.
An ZhuDepartment of Pediatrics, Second People's Hospital of Jinyun County (Huzhen Branch of Lishui Central Hospital), Lishui City, Zhejiang Province, China.
Zhiyong ZhuDepartment of Infectious Diseases, Tonglu County Center for Disease Control and Prevention (Tonglu County Health Supervision Institute), Hangzhou City, Zhejiang Province, China.
Jinren PanDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, China.
Chaorong NiDepartment of Infectious Diseases, Wenzhou Center for Disease Control and Prevention (Wenzhou Health Supervision Institution), Wenzhou City, Zhejiang Province, China.
Wenjie WuDepartment of Infectious Diseases, Zhoushan Center for Disease Control and Prevention, Zhoushan City, Zhejiang Province, China.
An TangDepartment of Infectious Diseases, Zhoushan Center for Disease Control and Prevention, Zhoushan City, Zhejiang Province, China.
Lei GuoDepartment of Infection Control, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou City, Zhejiang Province, China.
Zhao YuDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, China.
Xicheng GuUniversity of Rochester, Rochester, New York, USA.
Yu ZhangTonglu Hospital of the First People's Hospital of Hangzhou, Hangzhou City, Zhejiang Province, China.
Xiaofei FuDepartment of Infectious Disease Control and Prevention, Jiaxing Center for Disease Control and Prevention, Jiaxing City, Zhejiang Province, China.
Yongqiang ShaoWenzhou Central Hospital, Wenzhou City, Zhejiang Province, China.
Shelan LiuDepartment of Infectious Diseases, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou City, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: Human respiratory syncytial virus (HRSV) coinfection with other respiratory pathogens frequently occurs in young children with acute respiratory illness. However, the epidemiological patterns and associated disease burden of HRSV coinfections in pediatric populations remain poorly characterized. What is added by this report?: Analysis of hospitalized children under 5 years in Zhejiang Province from 2018 to 2023 revealed that 20.4% experienced HRSV coinfections, with bacterial coinfections substantially exceeding viral coinfections (14.1% What are the implications for public health practice?: Implementation of comprehensive prevention strategies, including vaccination programs, nonpharmaceutical interventions, and enhanced surveillance of multiple respiratory pathogens, is essential to reduce HRSV coinfections and their associated disease burden during periods of high respiratory pathogen circulation.

Indexed as

Children Aged Under Five YearsCoinfectionDisease BurdenHuman Respiratory Syncytial Virus

Identifiers

PMID39931444
PMCPMC11807249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.