ArticleClinicoEconomics and outcomes research : CEOR2025
Atopic Dermatitis Treatments Before and After Initiation of Ruxolitinib Cream: 6-Month Follow-Up Analysis of a US Payer Claims Database.
Article in ClinicoEconomics and outcomes research : CEOR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Real-World Effect of Ruxolitinib Cream: Decreased Use of Additional Topical Therapies and Limited Escalation to Systemic Treatments.Advances in therapy · 2026Article
- Ruxolitinib Cream As-Needed Monotherapy Demonstrates Sustained Disease and Symptom Control in Patients with Mild to Moderate Atopic Dermatitis: Pooled Analysis from Two Phase 3 Studies.Dermatology and therapy · 2026Article
- Real-World Treatment Patterns in Patients with Atopic Dermatitis Initiating Ruxolitinib Cream: A 12-Month Follow-Up Analysis of a US Payer Claims Database.ClinicoEconomics and outcomes research : CEOR · 2026Article
- Use of Ruxolitinib Cream Results in Economic Benefits Compared with Dupilumab in Treatment of Patients with Atopic Dermatitis Meeting Severity Thresholds for Systemic Therapy.Dermatology and therapy · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Many patients with atopic dermatitis (AD), a highly pruritic, relapsing, inflammatory skin disease, experience inadequate disease control. Ruxolitinib cream was approved in the US in September 2021 for the treatment of mild-to-moderate AD. This analysis describes treatment patterns before and after initiation of ruxolitinib cream among patients with AD. Patients and Methods: This retrospective, observational study used medical and pharmacy claims data from the Healthcare Integrated Research Database (HIRD Results: Of 1,581 patients in the overall AD cohort, 749 had a history of more advanced AD therapy. During the follow-up period, 43.8% of patients did not receive any other AD treatment. Compared with baseline, fewer patients received topical corticosteroids (52.3% vs 30.4%), topical calcineurin inhibitors (13.9% vs 6.6%), and topical phosphodiesterase-4 inhibitors (4.4% vs 2.3%) during the follow-up period; slightly greater reductions were observed among the subset with a history of more advanced AD therapies. Oral corticosteroid use decreased from 20.9% to 15.5% overall and from 44.1% to 20.7% in the subset with more advanced baseline therapy. Among patients receiving biologics at baseline, 17.4% did not receive these treatments during the follow-up period. Conclusion: These 6-month follow-up data suggest that initiating ruxolitinib cream for AD may reduce the overall need for other topical treatments, oral corticosteroids, and biologics.
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