Evidence map›Paper›PMID 39931222›Full record

ArticleRadiology case reports2025

Acute soft head syndrome in sickle cell disease: A rare and under-recognized complication with diagnostic challenges.

Muhiddin Dervis, Adil Omer, Christopher Karakasis, David Mihal

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhiddin DervisCleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA.
Adil OmerCleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA.
Christopher KarakasisCleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA.
David MihalCleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute Soft Head Syndrome (ASHS) is an exceptionally rare complication of sickle cell disease (SCD), characterized by scalp pain and swelling secondary to subgaleal hematoma formation. Distinguishing its nonspecific clinical features, which often mimic other SCD-related complications, poses a significant diagnostic challenge. Imaging plays a crucial role in differentiating ASHS from other potential diagnoses and in evaluating the presence of coexisting intracranial hemorrhage, a common complication associated with ASHS. This report presents a rare case of ASHS in a patient with SCD, highlighting the diagnostic complexities and underscoring the essential role of imaging in its evaluation and management.

Indexed as

Acute Soft Head SyndromeEpidural HematomaSickle Cell DiseaseSubgaleal Hematoma

Identifiers

PMID39931222
PMCPMC11808609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.