Evidence map›Paper›PMID 39931188›Full record

ArticleIJID regions2025

Mortality Associated with Surgical Site Infections Following Cardiac Surgery: Insights from the International ID-IRI Study.

Hakan Erdem, Handan Ankarali, Jaffar A Al-Tawfiq, Kumar Angamuthu, Dragan Piljic, Ajdin Umihanic, Farouq Dayyab, Dilek Karamanlioğlu, Abdullah Umut Pekok, Meliha Cagla-Sonmezer and 37 more

Abstract read
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

47 authors.

Hakan ErdemTurkish Health Sciences University, Gülhane School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye.
Handan AnkaraliDepartment of Biostatistics and Medical Informatics, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Jaffar A Al-TawfiqSpecialty Internal Medicine and Quality and Patient Safety Department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Kumar AngamuthuDepartment of Infectious Diseases, Almana General Hospitals, Dammam, Saudi Arabia.
Dragan PiljicUniversity Clinical Center Tuzla, Department of Cardiovascular Surgery, Tuzla, Bosnia and Herzegovina.
Ajdin UmihanicUniversity Clinical Center Tuzla, Department of Cardiovascular Surgery, Tuzla, Bosnia and Herzegovina.
Farouq DayyabMohammed Bin Khalifa Bin Salman Al Khalifa Specialist Cardiac Centre, Awali, Bahrain.
Dilek KaramanlioğluEtlik City Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye.
Abdullah Umut PekokDepartment of Infectious Diseases, VM Medical Park, Pendik Hospital, Istanbul, Türkiye.
Meliha Cagla-SonmezerHacettepe University, School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye.
Amani El-KholyCairo University, Faculty of Medicine, Clinical and Chemical Pathology Department, Cairo, Egypt.
Maha Ali GadCairo University, Faculty of Medicine, Clinical and Chemical Pathology Department, Cairo, Egypt.
Lazar VelickiFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia and Institute of Cardiovascular Disease Vojvodina, Sremska Kamenica, Serbia.
Ozay AkyildizAcibadem Hospital, Department of Infectious Diseases and Clinical Microbiology, Adana, Türkiye.
Mustafa AltindisSakarya University, Faculty of Medicine, Department of Microbiology, Sakarya, Türkiye.
Dilşah Başkol-ElikEge University, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Izmir, Türkiye.
Buket Erturk-SengelMarmara University Pendik Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Türkiye.
İbrahim KaraSakarya University, Faculty of Medicine, Department of Cardiovascular Surgery, Sakarya, Türkiye.
Umit KahramanEge University, Faculty of Medicine, Department of Cardiovascular Surgery, Izmir, Türkiye.
Mehmet ÖzdemirNecmettin Erbakan University, Faculty of Medicine, Department of Microbiology, Konya, Türkiye.
Hulya CaskurluDepartment of Infectious Diseases and Clinical Microbiology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Yasemin CagDepartment of Infectious Diseases and Clinical Microbiology, Istanbul Medeniyet University Faculty of Medicine, Istanbul, Türkiye.
Abdulwahab Al-KhalifaUniversity Clinical Center Tuzla, Department of Cardiovascular Surgery, Tuzla, Bosnia and Herzegovina.
Atousa HakamifardInfectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Marina Kljaković-Gašpić BatinjanFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia and Institute of Cardiovascular Disease Vojvodina, Sremska Kamenica, Serbia.
Muhammad TahirDepartment of Medicine, Federal General Hospital, Islamabad, Pakistan.
Elif Tukenmez-TigenMarmara University Pendik Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Türkiye.
Joanna ZajkowskaMedical University in Bialystok, Department of Infectious Diseases and Neuroinfections, Bialystok, Poland.
Jehan ElKholyCairo University Hospital, Department of Anesthesia, Pain Management, Cairo, Egypt.
Hrvoje GašparovićUniversity Hospital Centre Zagreb, University of Zagreb, Department of Cardiac Surgery, Zagreb, Croatia.
Mine FilizTurkish Health Sciences University, Gülhane School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye.
Ozlem GulŞişli Hamidiye Etfal Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Türkiye.
Hamed Azhdari TehraniShahid Beheshti University of Medical Sciences, Department of Hematology and Medical Oncology, Tehran, Iran.
Elif Doyuk-KartalEskisehir Osmangazi University, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Eskisehir, Türkiye.
Yesim Aybar-BilirEtlik City Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Türkiye.
Hasip KahramanEskisehir Osmangazi University, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Eskisehir, Türkiye.
Hrvoje MikulićSKB Mostar, Department of Cardiac Surgery, Mostar, Bosnia and Herzegovina.
Saim DayanDicle University, School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Diyarbakir, Türkiye.
Antonio CascioDepartment of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE) - Infectious Disease Unit, Policlinico "P. Giaccone", University of Palermo, Palermo, Italy.
Eray Serdar YurdakulTurkish Health Sciences University, Gulhane School of Medicine, Department of Medical History and Ethics, Ankara, Türkiye.
Fatma ColkesenTurkish Health Sciences University, Konya Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology Konya, Türkiye.
Kadriye KarahangilIstanbul Medipol University Medical Faculty, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Türkiye.
Angel EspinosaMohammed Bin Khalifa Bin Salman Al Khalifa Specialist Cardiac Centre, Awali, Bahrain.
Bilal Ahmad RahimiKandahar University Faculty of Medicine, Department of Pediatrics, Kandahar, Afghanistan.
Zdraveski VangelPHI UC State Cardiac Surgery, Department of Cardiac Surgery, Skopje, North Macedonia.
Teresa FascianaDepartment of Health Promotion, Maternal Childhood, Internal Medicine of Excellence G. D'Alessandro, University of Palermo, Palermo, Italy.
Anna GiammancoDepartment of Health Promotion, Maternal Childhood, Internal Medicine of Excellence G. D'Alessandro, University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Surgical site infections (SSIs) after cardiac surgery increase morbidity and mortality rates. This multicenter study aimed to identify mortality risk factors associated with SSIs after heart surgery. Methods: Conducted from January to March 2023, this prospective study included 167 patients aged >16 years with post-heart surgery SSIs. The primary focus was the 30-day mortality. Univariate analysis and multivariate logistic regression utilizing the backward elimination method were used to establish the final model. Results: Several factors significantly correlated with mortality. These included urinary catheterization (odds ratio [OR] 14.197; 90% confidence interval [CI] 12.198-91.721]), emergent surgery (OR 8.470 [90% CI 2.028-35.379]), valvular replacement (OR 4.487 [90% CI 1.001-20.627]), higher quick Sequential Organ Failure Assessment scores (OR 3.147 [90% CI 1.450-6.827]), advanced age (OR 1.075 [90% CI 1.020-1.132]), and postoperative re-interventions within 30 days after SSI (OR 14.832 [90% CI 2.684-81.972]). No pathogens were isolated from the wound cultures of 53 (31.7%) patients. A total of 43.1% of SSIs (n = 72) were due to gram-positive microorganisms, whereas 27.5% of cases (n = 46) involved gram-negatives. Among the gram-positive bacteria, Conclusions: To mitigate mortality after heart surgery, stringent infection control measures and effective surgical antisepsis are crucial, particularly, in the elderly. The clinical progression of the disease is reflected by the quick Sequential Organ Failure Assessment score and patient re-intervention, and effective treatment is another essential component of SSI management.

Indexed as

CABGCardiacInfectionMortalitySurgical

Identifiers

PMID39931188
PMCPMC11808521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.