ArticleJournal of experimental orthopaedics2025
VELYS robotic-assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption.
Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Robot-assisted total knee arthroplasty and the risk of postoperative infection: a systematic review and meta-analysis.Journal of robotic surgery · 2026Pooled it
- Early clinical outcomes and preliminary radiological observations of VELYS-assisted versus conventional total knee arthroplasty: a meta-analysis.Journal of robotic surgery · 2026Pooled it
- Improved Accuracy With a Novel Imageless Robotic-Assisted System Versus Manual Instrumentation in Unicondylar Knee Arthroplasty: A Cadaveric Study.Arthroplasty today · 2026Article
- [Robotic knee arthroplasty-an evidence-based, narrative assessment of the current state].Orthopadie (Heidelberg, Germany) · 2026Review
- VELYS robotic-assisted solution achieves more accurate bone cutting and neutral ground mechanical axis compared with an accelerometer-based portable navigation system in ground kinematically aligned total knee arthroplasty.Knee surgery & related research · 2026Article
- Increased medial component gap at 30° flexion is associated with subjective instability and worse patient-reported outcomes after image-free robot-assisted total knee arthroplasty.Journal of experimental orthopaedics · 2026Article
- Robotic-Assisted Kinematically Aligned Total Knee Arthroplasty Demonstrated Early Rehabilitation and Select Mental Health-Related Quality of Life Improvements Compared to Conventional MA-TKA.Journal of clinical medicine · 2026Article
- [Research progress of robot-assisted total knee arthroplasty for valgus knee from perspective of precision medicine].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Robotic-assisted total knee replacement: a narrative review of evolution, clinical impact, and future prospects in AI-driven precision surgery.Annals of medicine and surgery (2012) · 2026Review
- Use of the VELYS Robotic-Assisted Solution in knee arthroplasty: A scoping review.Journal of experimental orthopaedics · 2026Review
- VELYS robotic-assisted total knee replacement leads to improved mobility, reduction in hospitalisation, surgical duration, and better psychological outcomes: a propensity score matched analysis.Arthroplasty (London, England) · 2025Article
- Novel all-intra-incisional pin placement technique in robotic total knee arthroplasty: a safer alternative.Arthroplasty (London, England) · 2025Article
- Advancements in Total Knee Arthroplasty over the Last Two Decades.Journal of clinical medicine · 2025Review
- Robotics total knee arthroplasty: is an image-based the only solution?Frontiers in surgery · 2025Review
- VELYS robotic-assisted total knee arthroplasty: Enhanced accuracy and comparable early outcomes versus manual instrumentation during adoption.Journal of experimental orthopaedics · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
Purpose: This study assessed the accuracy and early clinical outcomes of the VELYS™ Robotic-Assisted solution for total knee arthroplasty (TKA). Methods: A multicenter, prospective non-randomized 1:1 cohort study was conducted at five sites. Subjects underwent TKA with either manual instrumentation or with robotic-assistance (RA). RA procedures were the first conducted at each site, therefore, representing the adoption phase for each surgeon. Mechanical alignment was targeted in the manual arm, while the target and technique varied in the RA arm. The primary objective was a non-inferiority (NI) analysis of the accuracy of the hip-knee-ankle (HKA) for RA versus manual, with a 1.5° NI margin. The accuracy of the mechanical medial distal femoral angle (mMDFA), mechanical medial proximal tibial angle (mMPTA) tibial posterior slope (TPS) angles were measured. Adverse events (AEs) and patient-reported outcome measures (PROMs) were collected at 12 weeks and 1 year. Results: One hundred participants were recruited for both manual and RA groups, the mean preoperative demographics and PROM scores were similar. The primary endpoint NI analysis was successful ( Conclusions: This study found that the RA system can be safely adopted without adversely impacting the long leg alignment or increasing the risk of complications. Further, it was observed that the accuracy of the femoral and tibial component positioning was improved, and there were positive trends in the rate of serious AEs and some PROMs at early follow-up. Level of Evidence: Level II.
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