Evidence map›Paper›PMID 39931069›Full record

ArticleFrontiers in immunology2025

The utility of muscle magnetic resonance imaging in idiopathic inflammatory myopathies: a scoping review.

Julie J Paik, Lisa Christopher-Stine, Mikael Boesen, John A Carrino, S Peter Eggleton, Deborah Denis, Olga Kubassova

Abstract readScoping Review
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julie J PaikDepartment of Myositis, Johns Hopkins University, Baltimore, MD, United States.
Lisa Christopher-StineDepartment of Myositis, Johns Hopkins University, Baltimore, MD, United States.
Mikael BoesenIAG, Image Analysis Group, London, United Kingdom.
John A CarrinoDepartment of Radiology and Imaging, Weill Cornell Medicine, Hospital for Special Surgery, New York, NY, United States.
S Peter EggletonGlobal Clinical Development, Merck Serono Ltd., Feltham, United Kingdom, an affiliate of the healthcare business of Merck KGaA.
Deborah DenisGlobal Clinical Development, EMD Serono Research & Development Institute, Inc., Billerica, MA, United States, an affiliate of the healthcare business of Merck KGaA.
Olga KubassovaIAG, Image Analysis Group, London, United Kingdom.

Funding

Skeletal Myopathy in Systemic Sclerosis: Devising a Classification Schema Predictive of OutcomesK23AR073927 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI PAIK, JULIE JISUN · 2020 to 2024
$787k
NIAMS NIH HHS K23 AR073927
6 · The paper itself

Abstract

Idiopathic inflammatory myopathies (IIMs) are muscle disorders characterized by proximal weakness of the skeletal muscles, inflammation in muscle, and autoimmunity. The classic subgroups in IIMs include dermatomyositis, inclusion body myositis, immune-mediated necrotizing myopathy, and polymyositis (PM). PM is increasingly recognized as a rare subtype and often included in overlap myositis, the antisynthetase syndrome when no rash is present, or misdiagnosed inclusion body myositis. Magnetic resonance imaging (MRI) has played an increasingly important role in IIM diagnosis and assessment. Although conventional MRI provides qualitative information that is helpful for diagnosis, its application for the quantitative assessment of disease activity is challenging. Therefore, advanced quantitative MRI techniques have been implemented in the past 10 years to highlight potential new applications of disease monitoring in IIM. The aim of this review is to examine the role of quantitative MRI techniques in evaluating the key imaging features of IIM, mainly muscle edema and muscle damage (fatty replacement and/or muscle atrophy).

Indexed as

Magnetic Resonance ImagingMuscle, SkeletalMyositisHumansdermatomyositisidiopathic inflammatory myopathiesmagnetic resonance imagingmyositispolymyositis

Identifiers

PMID39931069
PMCPMC11808160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.