Evidence map›Paper›PMID 39930783›Full record

ReviewActa oncologica (Stockholm, Sweden)2025

Infantile undifferentiated sarcomas: a diagnostic and therapeutic challenge - two case reports and literature review.

Aleksandra Stanio, Jakub Czarny, Sandra Rutkowska, Katarzyna Adamczewska-Wawrzynowicz, Łukasz Młynarczyk, Agnieszka Stróżyk, Katarzyna Jończyk-Potoczna, Alicja Bartkowska-Śniatkowska, Jacek Wachowiak, Katarzyna Derwich and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Review in Acta oncologica (Stockholm, Sweden), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aleksandra Stanio *Student Scientific Circle, Poznan University of Medical Sciences, Poland.
Jakub Czarny *Student Scientific Circle, Poznan University of Medical Sciences, Poland.
Sandra RutkowskaDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland.
Katarzyna Adamczewska-WawrzynowiczDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland.
Łukasz MłynarczykDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland.
Agnieszka StróżykDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland.
Katarzyna Jończyk-PotocznaDepartment of Pediatric Radiology, Poznan University of Medical Sciences, Poland.
Alicja Bartkowska-ŚniatkowskaDepartment of Pediatric Anaesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poland.
Jacek WachowiakDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland.
Katarzyna DerwichDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland.
Olga Zając-SpychałaDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poland. olga_zajac@wp.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSoft tissue undifferentiated sarcomas (STUS) are an ultra-rare and heterogenous group of mesenchymal neoplasms often lacking known genetic abnormalities with a marked vulnerability towards intensive therapy such as invasive surgery and high dose chemotherapy. Despite aggressive treatment, they are usually associated with dismal outcomes. CASE PRESENTATION: Here we describe two cases of STUS in 3-week-old and 3-month-old infants localized on the neck and the trunk area. DISCUSSION: In both cases, the malignancy had a fatal outcome due to the toxicity of intensive therapy in one case and the progression of the disease in the other. The purpose of this report is to discuss the clinical challenges of managing infancy-related STUS such as limited treatment options and poor prognosis.

Indexed as

SarcomaSoft Tissue NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsFatal OutcomeHumansInfantInfant, Newborn

Identifiers

PMID39930783
PMCPMC11833329

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.