ArticleThoracic research and practice2025
Latent Tuberculosis Infection in Inflammatory Rheumatic Diseases Before Biological and Synthetic DMARD Treatment: Results from Three Rheumatology Centers in Different Regions of Türkiye.
Article in Thoracic research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Risk factors and prevalence of latent tuberculosis infection in rheumatic patients: a meta-analysis.BMC infectious diseases · 2025Pooled it
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study was to investigate the prevalence of latent tuberculosis (TB) infection (LTBI) and its associated factors in patients with inflammatory rheumatic diseases (IRDs) prior to the administration of biologic and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs/tsDMARDs). MATERIAL AND
methodsA total of 402 patients with IRDs who were receiving bDMARDs/tsDMARDs from tertiary rheumatology centers in three different geographical regions were included in the study. Demographic, clinical, and TB-related characteristics were documented. The patients were divided into two groups, namely those with LTBI and non-LTBI, and their data were subjected to comparative analysis. The impact of various factors on LTBI was evaluated by regression analysis.
resultsThe prevalence of LTBI was 50.7% (204/402) before bDMARD/tsDMARD therapy. The proportion of male patients [108 (52.9%) vs. 84 (42.3%);
conclusionThe present study demonstrated that more than half of patients with IRDs undergoing advanced therapies have LTBI, with this infection being associated with male sex, smoking status, and duration of bDMARD use. Furthermore, this study indicates that appropriate screening and treatment of LTBI in patients with rheumatic diseases are associated with favorable clinical outcomes.
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