ArticleVox sanguinis2025
Preliminary determination of bacterial contamination of whole blood units in a Ghanaian blood bank: Providing evidence to improve transfusion safety.
Article in Vox sanguinis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- Article
- Bacterial Contamination in Stored Blood for Transfusion and Associated Infectious Risks Among Patients with Cancer at Mbarara Regional Referral Hospital, in Uganda.Journal of blood medicine · 2026Article
- Preliminary determination of bacterial contamination of whole blood units in a Ghanaian blood bank: Providing evidence to improve transfusion safety.Vox sanguinis · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND AND
objectivesTransfusion-associated bacterial sepsis poses a significant risk to patient safety. This study aimed to determine the rate of bacterial contamination of whole blood (WB) collected at the Cape Coast Teaching Hospital (CCTH) as a quality control and quality assurance activity. MATERIALS AND
methodsOne-hundred and three WB units collected between January and April of 2018 were screened for bacterial contamination. Bacteria isolated from positive cultures were identified and subjected to antimicrobial testing. WB recipients were followed up for clinical symptoms.
resultsOf the 103 WB units tested, 33 (32%) were contaminated with bacteria. Gram-positive organisms accounted for 67% of the isolates, including coagulase-negative Staphylococcus, Staphylococcus aureus and Bacillus spp., while Gram-negative bacteria comprised 33% of the isolates, with Citrobacter freundii, Serratia marcescens, Escherichia coli and Providencia stuartii being identified. Resistance to antibiotics varied between species. No septic transfusion events were reported involving WB units tested in this study.
conclusionThe high percentage of contaminated WB units collected at the CCTH provided evidence-based data for the implementation of improved donor skin disinfection processes and the use of blood diversion pouches in 2019. These approaches allowed CCTH to comply with Ghanaian regulatory entities.
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