Evidence map›Paper›PMID 39930527›Full record

SynthesisScandinavian journal of trauma, resuscitation and emergency medicine2025

Prognostic accuracy of point-of-care ultrasound in patients with pulseless electrical activity: a systematic review and meta-analysis.

Shang-Jun Zhang Jian, Tzu-Heng Cheng, Chieh-Ching Yen

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scandinavian journal of trauma, resuscitation and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shang-Jun Zhang JianDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Tzu-Heng ChengDepartment of Emergency Medicine, New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan.
Chieh-Ching YenDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan. chiehching74@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognosis for pulseless electrical activity (PEA) is typically poor; however, patients with cardiac activity observed on point-of-care ultrasound (POCUS) tend to have better outcomes compared to those without. This systematic review and meta-analysis were conducted to assess the prognostic accuracy of cardiac activity detected by POCUS in predicting resuscitation outcomes in patients experiencing PEA.

methodsA comprehensive literature search was conducted in PubMed, Embase, and the Cochrane Central Register of Controlled Trials to identify relevant studies. The pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio, and the area under the summary receiver operating characteristic curve (SROC) were calculated using the bivariate model.

resultsEighteen studies comprising 1202 patients were included in the meta-analysis. Cardiac activity observed on POCUS demonstrated a pooled sensitivity of 0.86 (95% CI 0.67-0.95) and specificity of 0.64 (95% CI 0.51-0.75) for predicting return of spontaneous circulation, a pooled sensitivity of 0.89 (95% CI 0.80-0.94) and specificity of 0.73 (95% CI 0.63-0.81) for survival to admission (SHA), and a pooled sensitivity of 0.79 (95% CI 0.58-0.91) and specificity of 0.58 (95% CI 0.47-0.68) for survival to discharge. The highest area under the SROC, 0.89 (95% CI 0.86-0.92), was observed for SHA.

conclusionsOur study suggests that POCUS may serve as a vital component of a multimodal approach for early termination of resuscitation.

Indexed as

Heart ArrestPoint-of-Care SystemsCardiopulmonary ResuscitationHumansPrognosisUltrasonographyCardiac arrestMeta-analysisPoint-of-care ultrasoundPulseless electrical activity

Identifiers

PMID39930527
PMCPMC11812266

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.