Evidence map›Paper›PMID 39930265›Full record

ArticleCardiovascular engineering and technology2025

Performance Comparison of Centered and Tilted Blunt and Lighthouse Tip Cannulae for Drainage in Extracorporeal Life Support.

Federico Rorro, Lars Mikael Broman, Lisa Prahl Wittberg

Abstract readComparative Study
In one paragraph

Article in Cardiovascular engineering and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Federico RorroFLOW, Department of Engineering Mechanics, KTH Royal Institute of Technology, Stockholm, Sweden. rorro@kth.se.ORCID 0000-0002-8061-4146
Lars Mikael BromanECMO Centre Karolinska, Pediatric Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Lisa Prahl WittbergFLOW, Department of Engineering Mechanics, KTH Royal Institute of Technology, Stockholm, Sweden.

Funding

European Research Council 101045453
6 · The paper itself

Abstract

introductionExtracorporeal membrane oxygenation is a lifesaving treatment for patients with refractory acute respiratory, circulatory, or combined cardiopulmonary failure. The patient is cannulated with one or two cannulae for drainage and reinfusion of blood. Blood is drained from the patient, pumped through a membrane lung for oxygenation and returned to the patient. Treatment efficiency depends on correct cannula positioning and interactions between drainage and reinfusion cannula.

methodsAn experimental setup was built to study the isolated drainage performance of 24 Fr rigid models of a blunt and lighthouse tip cannula, both when centered and when tilted towards the vessel wall. Planar particle image velocimetry was used to investigate the flow field with water as the fluid medium.

resultsFor similar flow configuration, higher shear stresses were recorded in the blunt tip rather than lighthouse tip cannula. Moreover, in the lighthouse tip cannula, side-holes furthest from the tip (proximal side-holes) had the highest drainage. Results did not change substantially when the cannula was tilted towards the vessel wall.

conclusionsThe effective drainage point of the lighthouse tip cannula was located near the proximal side-holes. Lower shear stresses were recorded in the lighthouse tip cannula when compared with the blunt tip cannula, for all considered flow rate ratios and cannula positions.

Indexed as

CannulaDrainageExtracorporeal Membrane OxygenationEquipment DesignHumansModels, CardiovascularRheologyStress, MechanicalCannulaDrainageExtracorporeal membrane oxygenation (ECMO)Particle image velocimetry (PIV)

Identifiers

PMID39930265
PMCPMC11933157

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