Evidence map›Paper›PMID 39930237›Full record

ReviewAdvances in experimental medicine and biology2025

NUDC Is Critical for Mitosis and Postmitotic Cell Maintenance Through Its Modulation of Dynein and Actin Cytoskeletal Reorganization.

Mary Anne Garner, Alecia K Gross

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary Anne GarnerDepartment of Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Alecia K GrossDepartment of Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. agross@uab.edu.

Funding

Rhodopsin Trafficking and Retinal DegenerationsR01EY019311 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GROSS, ALECIA K · 2008 to 2012
$1.9M
Photoreceptor Disk Formation and Retinal DegenerationsR01EY030096 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GROSS, ALECIA K · 2020 to 2023
$1.8M
NEI NIH HHS R01 EY019311NEI NIH HHS R01 EY030096
6 · The paper itself

Abstract

Nuclear Distribution Protein C (NUDC) has been studied extensively for its role in mitosis. In addition to its well-established role in dynein-mediated nuclear migration, NUDC also plays a role in postmitotic cells. NUDC affects dynein-mediated protein and organelle trafficking and also stabilizes the actin-modulating protein, cofilin (CFL1), thereby affecting cytoskeletal reorganization. This mini-review will cover the known role of NUDC in mitosis as well as its role in actin cytoskeletal reorganization and in protein and organelle trafficking in nondividing cells, as well as update findings on the effect of a loss of NUDC on rod photoreceptors.

Indexed as

Actin CytoskeletonActinsCell Cycle ProteinsDyneinsMitosisNuclear ProteinsAnimalsHumansRetinal Rod Photoreceptor CellsActinsCell Cycle ProteinsDyneinsNuclear ProteinsCofilin 1 (CFL1)DyneinMitosisNUDCPhotoreceptorRetinal degenerationRod

Identifiers

PMID39930237
PMCPMC13182845

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.