ReviewAdvances in experimental medicine and biology2025
RPE Basal Lamina Biology and Pathophysiology Related to Age-Related Macular Degeneration.
Review in Advances in experimental medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Diagnostic Performance of Ring Aperture Retro Mode Imaging for Detecting Pigment Migration in Age-Related Macular Degeneration.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Age-related macular degeneration (AMD) is a progressive eye disease that primarily affects the central part of the retina and is a leading cause of vision impairment worldwide (Wong WL, Su X, Li X, Lancet Glob Health 2:e106-116, 2014). Sub-retinal pigment epithelium (RPE) deposits represent a broadly defined term encompassing compositionally and anatomically distinct protein and lipid aggregates (i.e., drusen, basal linear deposits [BLinDs], and basal laminar deposits [BLamDs]). These deposits play a pivotal role in the pathogenesis of AMD and act as both key indicators and contributors to disease progression (van der Schaft TL, de Bruijn WC, Mooy CM, de Jong PT, Graefes Arch Clin Exp Ophthalmol 231:470-475, 1993; Sarks SH, Arnold JJ, Killingsworth MC, Sarks JP, Br J Ophthalmol 83:358-368, 1999; Sura AA, Chen L, Messinger JD, Invest Ophthalmol Vis Sci 61:19, 2020). Thus, understanding factors that influence sub-RPE deposit formation is crucial, especially in the context of retinal health and disease (Loeffler KU, Lee WR, Br J Ophthalmol 82:1104-1105, 1998; Sarks SH, Arnold JJ, Killingsworth MC, Sarks JP, Br J Ophthalmol 83:358-368, 1999). In this mini review, we have gathered and discussed valuable insights to provide a comprehensive overview focusing on BLamDs and their relevance to retinal disease.
Indexed as
Identifiers
39930166What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.