ArticleScientific reports2025
The effects of experimental conditions on extraction of polyphenols from African Nutmeg peels using NADESs-UAE: a multifactorial modelling technique.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Cascade Valorisation of Lemon-Processing Residues (Part I): Current Trends in Green Extraction Technologies and High-Value Bioactive Recovery.Foods (Basel, Switzerland) · 2026Review
- Effect of freeze-pressure regulated extraction technology on the physicochemical properties and pharmacological activities of guizhi extract.Frontiers in chemistry · 2025Article
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Abstract
Extraction of polyphenolic compounds from African nutmeg (Monodora myristica (Gaertn.)) peels using natural acidic deep eutectic solvents coupled to ultrasound-assisted extraction (NADESs-UAE) followed many factors at a time (MFAT) screening with response surface optimization was investigated. Fourteen different NADESs based on citric acid as hydrogen bond acceptor (HBA) were designed and tested. Sucrose, fructose, xylitol, glycerol, glycine, and glucose were used as hydrogen bond donors (HBDs). The responses studied are total phenolic compounds (TPC), total flavonoid compounds (TFC), and antioxidant activity (AA) based on cupric ion reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP). The UAE procedure was optimized with the most efficient NADES. Quadratic models produced satisfactory fitting of the experimental data regarding TPC (R
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