Evidence map›Paper›PMID 39930019›Full record

ArticleBrain imaging and behavior2025

Regional high iron deposition on brain quantitative susceptibility mapping correlates with cognitive decline in chronic kidney disease patients.

Yuan Li, Yuhan Jiang, Bingbing Gao, Na Liu, Yukun Zhang, Huiling Zhou, Qingwei Song, Nan Wang, Yanwei Miao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain imaging and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan Li *Department of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.ORCID https://orcid.org/0009-0002-5426-2703
Yuhan Jiang *Department of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.ORCID http://orcid.org/0000-0002-5669-377X
Bingbing GaoDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.
Na LiuDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.
Yukun ZhangDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.
Huiling ZhouDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.
Qingwei SongDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.
Nan WangDepartment of Nephrology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China.
Yanwei MiaoDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Xigang District, Dalian, Liaoning, 116011, China. ywmiao716@163.com.ORCID https://orcid.org/0000-0003-3103-9824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate changes in gray matter nuclei iron deposition in chronic kidney disease (CKD) patients using the quantitative susceptibility mapping (QSM) threshold method, and analyze the relationship between brain iron levels and cognitive function. A total of fifty-three CKD patients were prospectively recruited, comprising 35 hemodialysis (HD, 57.54 ± 10.42 years, 21 males) and 18 non-hemodialysis (NHD, 55.06 ± 11.47 years, 10 males ), and were compared to 43 healthy controls (HC, 55.67 ± 7.79 years, 18 males). All participants underwent clinical assessments, neuropsychological tests, and QSM scans. The mean magnetic susceptibility value (MSV) and volume of the whole nuclei (MSV

Indexed as

BrainCognitive DysfunctionIronRenal Insufficiency, ChronicAdultAgedBrain MappingCognitionFemaleGray MatterHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsProspective StudiesIronChronic kidney diseaseCognitive dysfunctionGray matter nucleiIron overloadQuantitative susceptibility mapping

Identifiers

PMID39930019
PMCPMC11978685

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.