ArticleAesthetic plastic surgery2025
Autologous Fat Grafting for the Treatment of Structural Infraorbital Dark Circles.
Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Advancing fat graft survival: from adipose-derived stem cell mechanisms to next-generation regenerative strategies.Frontiers in cell and developmental biology · 2026Review
- A Real-World Study of Polynucleotides HPT for Treating Periorbital Hyperpigmentation.Clinical, cosmetic and investigational dermatology · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfraorbital dark circles have become a troubling issue for many young people, giving a tired and aged appearance. A significant portion of these dark circles is caused by structural deformities in the lower eyelid area. Many treatment methods have been introduced for the treatment of structural dark circles (SDC). Among the treatment options, autologous fat grafting appears to be an effective approach for treating SDC in young individuals.
methodsThis study evaluated patients with SDC who underwent autologous fat grafting between December 2021 and August 2023. The proposed technique involved a deep-level ligament releasing injection using micro-fat, while the superficial layer was treated with stromal vascular fraction gel extracted from the micro-fat.
resultsA total of 88 patients enrolled in the study had an average age of 25.4 ± 3.1 years. Throughout the follow-up period (averaging 11.2 months), notable improvements in SDC and tear trough deformity were maintained without any major complications. Patient satisfaction, as self-assessed post-procedure questionnaires, revealed that 40.9% were very satisfied, 56.8% were satisfied, and 2.3% were neutral regarding the outcomes.
conclusionsThe autologous fat grafting technique we proposed is both effective and reliable, offering high patient satisfaction with minimal risk of complications. Long-term results have proved its effectiveness for young individuals with SDC. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.