Evidence map›Paper›PMID 39929973›Full record

ArticleNature microbiology2025

Upcycling of polyamides through chemical hydrolysis and engineered Pseudomonas putida.

Jan de Witt, Tom Luthe, Johanna Wiechert, Kenneth Jensen, Tino Polen, Astrid Wirtz, Stephan Thies, Julia Frunzke, Benedikt Wynands, Nick Wierckx

Abstract read
In one paragraph

Article in Nature microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Microbial plastic degradation: enzymes, pathways, challenges, and perspectives.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  10. Data-driven synthetic microbes for sustainable future.NPJ systems biology and applications · 2025
    Review
  11. An Update: Enzymatic Synthesis for Industrial Applications.Angewandte Chemie (International ed. in English) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jan de WittInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0003-2799-1097
Tom LutheInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Johanna WiechertInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Kenneth JensenNovonesis A/S, Biologiens Vej 2, Kgs, Lyngby, Denmark.ORCID http://orcid.org/0000-0001-6286-5577
Tino PolenInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Astrid WirtzInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Stephan ThiesInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0003-4240-9149
Julia FrunzkeInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0001-6209-7950
Benedikt WynandsInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Nick WierckxInstitute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany. n.wierckx@fz-juelich.de.ORCID http://orcid.org/0000-0002-1590-1210

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 458090666EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101044949EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 870294EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 887711EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 953073
6 · The paper itself

Abstract

Aliphatic polyamides, or nylons, are widely used in the textile and automotive industry due to their high durability and tensile strength, but recycling rates are below 5%. Chemical recycling of polyamides is possible but typically yields mixtures of monomers and oligomers which hinders downstream purification. Here, Pseudomonas putida KT2440 was engineered to metabolize C

Indexed as

Metabolic EngineeringNylonsPseudomonas putidaBacterial ProteinsCaprolactamCupriavidus necatorHydrolysisHydroxybutyratesMetabolic Networks and PathwaysOperonBacterial ProteinsCaprolactamHydroxybutyratesNylons

Identifiers

PMID39929973
PMCPMC11879879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.