Evidence map›Paper›PMID 39929538›Full record

SynthesisBMJ global health2025

Impact of measles vaccination strategies on vaccination rates in low-income and middle-income countries: a systematic review and meta-analysis.

Kiddus Yitbarek, Abela Mahimbo, Firew Tekle Bobo, Mirkuzie Woldie, Meru Sheel, Jane Frawley, Andrew Hayen

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kiddus YitbarekDepartment of Health Policy and Management, Faculty of Public Health, Jimma University, Jimma, Ethiopia kiddus.yitbarek@yahoo.com.ORCID http://orcid.org/0000-0002-4935-6871
Abela MahimboSchool of Public Health, Faculty of Health, University of Technology Sydney, Ultimo, New South Wales, Australia.
Firew Tekle BoboFenot Project, Department of Global Health and Population, Harvard T H Chan School of Public Health, Addis Ababa, Ethiopia.
Mirkuzie WoldieDepartment of Health Policy and Management, Faculty of Public Health, Jimma University, Jimma, Ethiopia.
Meru SheelSydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0001-5453-070X
Jane FrawleySchool of Public Health, Faculty of Health, University of Technology Sydney, Ultimo, New South Wales, Australia.
Andrew HayenSchool of Public Health, Faculty of Health, University of Technology Sydney, Ultimo, New South Wales, Australia.ORCID http://orcid.org/0000-0003-4046-8030

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWhile many interventions aim to raise measles vaccination coverage in low-income and middle-income countries (LMICs), their overall effectiveness and cost-effectiveness are unknown. We did a review to identify and synthesise scientific research that evaluated the impact and cost-effectiveness of measles vaccination strategies on measles vaccination coverage, timeliness, hospitalisation rates, and mortality.

methodsIn this review, we searched for English-language articles published between 2012 and July 2023 in eight databases, including PubMed, ProQuest, MEDLINE (Ovid), Embase (Ovid), CINAHL, Scopus, Web of Science and the Cochrane Database of Systematic Reviews. We also included relevant grey literature sources. The review focused on studies evaluating the impact of vaccination strategies on vaccination-related outcomes in children under 5. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines throughout the process, we used Covidence software to manage most review activities. Two independent reviewers screened articles, assessed their quality using the Joanna Briggs Institute guidelines and extracted data using a predefined electronic tool. We predetermined measles vaccination coverage and timeliness as the primary outcomes, with hospitalisation and mortality as secondary outcomes. A random-effects model was employed for the meta-analysis.

resultsWe identified 44 articles, of which 14 were included in the meta-analysis. The meta-analysis indicated that vaccination-targeting interventions such as vaccination reminders, cash incentives, community engagement and health education activities increase measles vaccination coverage (RR 1.19, 95% CI 1.10 to 1.27). Our analysis also indicated that interventions such as vaccine reminders, educational programmes and incentives improved timely vaccination. Furthermore, we identified cost-effective strategies such as geographically informed microplanning, unrestricted vial opening, supplementary immunisation activities, community engagement, outreach programmes and financial incentives.

conclusionMost of the identified vaccination interventions significantly improve measles vaccination coverage and timeliness in LMICs while remaining cost-effective. Tailoring these interventions to local contexts is crucial for maximising their effectiveness in protecting children from measles and its adverse consequences. PROSPERO REGISTRATION NUMBER: CRD42023433125.

Indexed as

Developing CountriesImmunization ProgramsMeaslesMeasles VaccineVaccinationVaccination CoverageCost-Benefit AnalysisHumansMeasles VaccineMeaslesPublic HealthVaccines

Identifiers

PMID39929538
PMCPMC11815466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.